Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 5/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | MITF | O75030 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24795907 | 0.97 | HPGD (0.43) | HPGDSMN1; SMN2LMNAKMT2AALDH1A1 | |
| SCHEMBL24796282 | 0.96 | HPGD (0.47) | HPGDSMN1; SMN2LMNAKMT2AALDH1A1 | |
| SCHEMBL24796631 | 0.94 | HTT (0.44) | HPGDSMN1; SMN2LMNAKMT2AALDH1A1 | |
| SCHEMBL21389191 | 0.86 | HPGD (0.44) | HPGDSMN1; SMN2LMNAKMT2AALDH1A1 | |
| SCHEMBL21389152 | 0.86 | HPGD (0.41) | HPGDSMN1; SMN2LMNAKMT2AALDH1A1 | |
| SCHEMBL21389295 | 0.86 | HPGD (0.41) | HPGDSMN1; SMN2LMNAKMT2AALDH1A1 | |
| SCHEMBL24796302 | 0.85 | HPGD (0.44) | HPGDSMN1; SMN2LMNAKMT2AALDH1A1 | |
| SCHEMBL24796394 | 0.85 | HPGD (0.41) | HPGDSMN1; SMN2LMNAKMT2AALDH1A1 | |
| SCHEMBL21389261 | 0.85 | ATM (0.50) | HPGDSMN1; SMN2LMNAKMT2AALDH1A1 | |
| SCHEMBL24796138 | 0.84 | HPGD (0.41) | HPGDSMN1; SMN2LMNAKMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019183577-A1 | MODULATORS OF G-PROTEIN COUPLED RECEPTORS | CARMOT THERAPEUTICS, INC. (US) | 2019-09-26 | — | — | WO | disclosed |