⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Cyclohexane SCHEMBL17939525 | 0.85 | — | — | |
| SCHEMBL7774044 | 0.85 | — | — | |
| SCHEMBL36991 | 0.84 | — | — | |
| SCHEMBL11183068 | 0.84 | — | — | |
| SCHEMBL22129636 | 0.84 | — | — | |
| SCHEMBL6065835 | 0.84 | — | — | |
| SCHEMBL81839 | 0.84 | — | — | |
| SCHEMBL10801124 | 0.81 | — | — | |
| Methane SCHEMBL4558431 | 0.80 | — | — | |
| SCHEMBL1275896 | 0.80 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109776414-B | Bcl-2 protein inhibitor and preparation method and application thereof | 山东大学 | 2022-04-22 | — | — | CN | disclosed |
| US-8552000-B2 | Therapeutic agent for senile dementia | DAINIPPON SUMITOMO PHARMA CO., LTD. (JP) | 2013-10-08 | — | — | US | disclosed |
| US-20120165341-A1 | THERAPEUTIC AGENT FOR SENILE DEMENTIA | DAINIPPON SUMITOMO PHARMA CO., LTD. | 2012-06-28 | — | — | US | disclosed |
| US-8148379-B2 | Use of lurasidone (N-[(1R,2R)-2-[4-(1,2-benzisothiazol-3-yl)-1-piperazinyl-methyl]-1-cyclohexylmethyl]-2,3-bicycl[2.2.1]heptanedicarboxyimide) | DAINIPPON SUMITOMO PHARMA CO., LTD. (JP) | 2012-04-03 | — | — | US | disclosed |
| US-7638532-B2 | 3-aryloxy-8-aza-bicyclo[3.2.1]oct-6-ene derivatives and their use as monoamine neurotransmitter re-uptake inhibitors | NEUROSEARCH A/S (DK) | 2009-12-29 | — | — | US | disclosed |
| US-20090030035-A1 | 3-Aryloxy-8-aza-bicyclo[3.2.1]]oct-6-ene derivatives and their use as monoamine neurotransmitter re-uptake inhibitors | NEUROSEARCH A/S (DK) | 2009-01-29 | — | — | US | disclosed |
| US-20080255148-A1 | Use of lurasidone (N-[(1R,2R)-2-[4-(1,2-benzisothiazol-3-yl)-1-piperazinyl-methyl]-1-cyclohexylmethyl]-2,3-bicycl[2.2.1]heptanedicarboxyimide) | DAINPPON SUMITOMO PHARMA CO., LTD. (JP) | 2008-10-16 | — | — | US | disclosed |
| US-20060142276-A1 | Therapeutic agent for senile dementia | DAINIPPON SUMITOMO PHARMA CO. LTD. (JP) | 2006-06-29 | — | — | US | disclosed |
| EP-1637530-A1 | THERAPEUTIC AGENT FOR SENILE DEMENTIA | Dainippon Sumitomo Pharma Co., Ltd. (JP) | 2006-03-22 | — | — | EP | disclosed |
| EP-0464846-B1 | Imide derivatives, and their production and use | SUMITOMO PHARMA (JP) | 1998-04-22 | — | — | EP | disclosed |
| EP-0384694-B1 | Sheet or film of cyclo-olefin polymer | MITSUI PETROCHEMICAL IND (JP) | 1996-09-18 | — | — | EP | disclosed |
| US-5532372-A | Imide derivatives, and their production and use | SUMITOMO PHARMACEUTICALS COMPANY, LTD. (JP) | 1996-07-02 | — | — | US | disclosed |
| EP-0464846-A1 | Imide derivatives, and their production and use | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1992-01-08 | — | — | EP | disclosed |
| EP-0384694-A2 | Sheet or film of cyclo-olefin polymer | MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) | 1990-08-29 | — | — | EP | disclosed |
| US-4814490-A | Organopalladium approaches to prostaglandins | IOWA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (US) | 1989-03-21 | — | — | US | disclosed |
| US-4113755-A | REACTING A NORBORNENE WITH AN ALKENYL MERCURIC HALIDE AND NOBLE METAL SALT | IOWA STATE UNIVERSITY RESEARCH FOUNDATION (US) | 1978-09-12 | — | — | US | disclosed |