Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21389134 | 0.84 | KMT2A (0.46) | KMT2AKDM4EMAPK1POLBTSHR | |
| SCHEMBL24796119 | 0.77 | KDM4E (0.48) | KMT2AKDM4EMAPK1POLBTSHR | |
| SCHEMBL24795970 | 0.76 | POLB (0.41) | KMT2AKDM4EMAPK1POLBTSHR | |
| SCHEMBL21389288 | 0.76 | KMT2A (0.44) | KMT2AKDM4EMAPK1POLBTSHR | |
| SCHEMBL21389457 | 0.75 | MAPK1 (0.49) | KMT2AKDM4EMAPK1TSHRMEN1 | |
| SCHEMBL21389186 | 0.75 | KDM4E (0.49) | KMT2AKDM4EMAPK1TSHRMEN1 | |
| SCHEMBL12424124 | 0.75 | KMT2A (0.55) | KMT2AMAPK1TSHRMEN1LMNA | |
| SCHEMBL21389353 | 0.75 | KMT2A (0.43) | KMT2AKDM4EMAPK1POLBTSHR | |
| SCHEMBL21389359 | 0.74 | KMT2A (0.48) | KMT2AKDM4EMAPK1POLBTSHR | |
| SCHEMBL24796270 | 0.74 | KMT2A (0.42) | KMT2AKDM4EMAPK1POLBMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019183577-A1 | MODULATORS OF G-PROTEIN COUPLED RECEPTORS | CARMOT THERAPEUTICS, INC. (US) | 2019-09-26 | — | — | WO | disclosed |