SCHEMBL21389601

SCHEMBL21389601

CCCCc1ccc2c3c(cccc13)C(=O)N(OS(=O)(=O)c1c(F)c(F)c(OC)c(F)c1F)C2=O

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ MAPT P10636 7/20 0.39
▸ KMT2A Q03164 6/20 0.39
▸ ELANE P08246 4/20 0.39
▸ MEN1 O00255 4/20 0.39
▸ POLB P06746 3/20 0.39
▸ L3MBTL1 Q9Y468 2/20 0.39
▸ CTSG P08311 2/20 0.39
▸ KDM4E B2RXH2 7/20 0.38
▸ ALDH1A1 P00352 6/20 0.38
▸ HTT P42858 3/20 0.38
▸ XBP1 P17861 2/20 0.38
▸ LMNA P02545 2/20 0.38
▸ PABPC1 P11940 1/20 0.38
▸ NFKB1 P19838 1/20 0.38
▸ SMARCA2 P51531 1/20 0.38
▸ NFKB2 Q00653 1/20 0.38
▸ RELA Q04206 1/20 0.38
▸ PRMT1 Q99873 1/20 0.37
▸ TDP1 Q9NUW8 2/20 0.36
▸ HPGD P15428 5/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17146986 0.93 MAPT (0.43) MAPTKMT2AELANEMEN1POLB
SCHEMBL17231435 0.90 MAPT (0.38) MAPTKMT2AELANEMEN1POLB
SCHEMBL17146987 0.90 MAPT (0.38) MAPTKMT2AELANEMEN1POLB
SCHEMBL17231444 0.88 MAPT (0.39) MAPTKMT2AELANEMEN1POLB
SCHEMBL19987620 0.86 TDP1 (0.41) MAPTKMT2AELANEMEN1CTSG
SCHEMBL17231430 0.84 MAPT (0.39) MAPTKMT2AELANEMEN1POLB
SCHEMBL19791315 0.81 KDM4E (0.43) MAPTKMT2AMEN1KDM4EALDH1A1
SCHEMBL17231438 0.80 TDP1 (0.44) MAPTKMT2AELANEMEN1POLB
SCHEMBL19999244 0.79 KDM4E (0.56) MAPTKMT2AMEN1KDM4EALDH1A1
SCHEMBL17231427 0.79 KDM4E (0.61) MAPTKMT2AELANEMEN1POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11754920-B2 Thermal acid generator and resist composition using same ADEKA CORPORATION (JP) 2023-09-12 — — US disclosed
US-20220197136-A1 THERMAL ACID GENERATOR AND RESIST COMPOSITION USING SAME ADEKA CORPORATION (JP) 2022-06-23 — — US disclosed
US-20200183271-A1 THERMAL ACID GENERATOR AND RESIST COMPOSITION USING SAME ADEKA CORPORATION (JP) 2020-06-11 — — US disclosed
US-20190294044-A1 POSITIVE PHOTOSENSITIVE COMPOSITION, PATTERN USING SAME, AND METHOD OF MANUFACTURING PATTERN ADEKA CORPORATION (JP) 2019-09-26 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200183271-A1 THERMAL ACID GENERATOR AND RESIST COMPOSITION USING SAME ACSL1, GAR1, LRBA MAPT 3932/4885KMT2A 1808/4885ELANE 4578/4885
US-11754920-B2 Thermal acid generator and resist composition using same ACSL1, LRBA, GAR1 MAPT 4032/4885KMT2A 1839/4885ELANE 4549/4885
US-20220197136-A1 THERMAL ACID GENERATOR AND RESIST COMPOSITION USING SAME ACSL1, LRBA, GAR1 MAPT 4032/4885KMT2A 1839/4885ELANE 4549/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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