⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24669198 | 0.79 | — | — | |
| SCHEMBL23721309 | 0.75 | — | — | |
| SCHEMBL16656730 | 0.74 | — | — | |
| SCHEMBL10283960 | 0.74 | — | — | |
| SCHEMBL20150462 | 0.73 | — | — | |
| SCHEMBL23284570 | 0.72 | — | — | |
| SCHEMBL20820673 | 0.70 | — | — | |
| SCHEMBL12879752 | 0.70 | — | — | |
| SCHEMBL27064422 | 0.70 | — | — | |
| SCHEMBL25914585 | 0.68 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022125804-A1 | SMARCA DEGRADERS AND USES THEREOF | KYMERA THERAPEUTICS, INC. (US) | 2022-06-16 | — | — | WO | disclosed |
| US-20190292157-A1 | NOVEL HETEROCYCLIC COMPOUNDS AS INHIBITORS OF VANIN-1 ENZYME | PFIZER INC. (US) | 2019-09-26 | — | — | US | disclosed |