Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 1/20 | 0.51 |
| ▸ | SRC | P12931 | 1/20 | 0.51 |
| ▸ | CD38 | P28907 | 2/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.46 |
| ▸ | HSP90B1 | P14625 | 1/20 | 0.46 |
| ▸ | ACP1 | P24666 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.42 |
| ▸ | P2RX7 | Q99572 | 3/20 | 0.42 |
| ▸ | HSD17B13 | Q7Z5P4 | 1/20 | 0.40 |
| ▸ | CNR1 | P21554 | 1/20 | 0.40 |
| ▸ | CNR2 | P34972 | 1/20 | 0.40 |
| ▸ | AURKA | O14965 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2137279 | 0.89 | ABL1 (0.49) | ABL1SRCCD38CYP3A4HSP90AA1 | |
| SCHEMBL2136868 | 0.87 | ABL1 (0.47) | ABL1SRCCD38CYP3A4HSP90AA1 | |
| SCHEMBL2134833 | 0.85 | HSP90AA1 (0.43) | CYP3A4HSP90AA1HSP90B1KDM4EALDH1A1 | |
| SCHEMBL2137198 | 0.84 | ABL1 (0.47) | ABL1SRCCD38CYP3A4HSP90AA1 | |
| SCHEMBL2140565 | 0.83 | ABL1 (0.48) | ABL1SRCCD38HSP90AA1HSP90B1 | |
| SCHEMBL2137639 | 0.83 | BCHE (0.49) | ABL1SRCHSP90AA1HSP90B1KDM4E | |
| SCHEMBL2137266 | 0.80 | HTT (0.51) | CYP3A4HTTKDM4EALDH1A1 | |
| SCHEMBL2135021 | 0.80 | CA1 (0.47) | CYP3A4HTTKDM4EALDH1A1HDAC1 | |
| SCHEMBL14700174 | 0.78 | SMN1; SMN2 (0.43) | CYP3A4HSP90AA1HSP90B1KDM4EALDH1A1 | |
| SCHEMBL2134013 | 0.77 | KCNQ3 (0.49) | CYP3A4KDM4EALDH1A1CNR1CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2445884-B1 | 4-AMINOPICOLINATES AND THEIR USE AS HERBICIDES | SYNGENTA LTD (GB) | 2013-02-13 | — | — | EP | disclosed |
| US-20120100990-A1 | 4 -AMINOPICOLINATES AND THEIR USE AS HERBICIDES | SYNGENTA CROP PROTECTION LLC (US) | 2012-04-26 | — | — | US | disclosed |
| US-20120100990-A1 | 4 -AMINOPICOLINATES AND THEIR USE AS HERBICIDES | SYNGENTA CROP PROTECTION LLC (US) | 2012-04-26 | — | — | US | disclosed |
| US-20120100990-A1 | 4 -AMINOPICOLINATES AND THEIR USE AS HERBICIDES | SYNGENTA CROP PROTECTION LLC (US) | 2012-04-26 | — | — | US | disclosed |
| WO-2010149956-A1 | 4 -AMINOPICOLINATES AND THEIR USE AS HERBICIDES | SYNGENTA LIMITED (GB) | 2010-12-29 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120100990-A1 | 4 -AMINOPICOLINATES AND THEIR USE AS HERBICIDES | DDT, DAO, NPM1 | ABL1 532/4885SRC 1958/4885CD38 4664/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.