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SCHEMBL21392338

SCHEMBL21392338

CC(=O)NCC(=O)NC1CCC(=O)NCCC(C(=O)N[C@@H](Cc2c[nH]c3ccccc23)C(N)=O)NC(=O)CNC(=O)C(Cc2ccccc2)NC(=O)[C@H](CCCN)NC1=O

nearest known ligand 0.57

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
▸ MC4R P32245 8/20 0.57
▸ MC1R Q01726 6/20 0.57
▸ SSTR5 P35346 5/20 0.47
▸ SSTR4 P31391 4/20 0.47
▸ SSTR2 P30874 3/20 0.47
▸ IL23R Q5VWK5 5/20 0.47
▸ SSTR1 P30872 3/20 0.46
▸ SSTR3 P32745 2/20 0.46
▸ REN P00797 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20362958 1.00 MC4R (0.57) MC4RMC1RSSTR5SSTR4SSTR2
SCHEMBL21392264 0.98 MC4R (0.57) MC4RMC1RSSTR5SSTR4SSTR2
SCHEMBL20206244 0.98 MC4R (0.57) MC4RMC1RSSTR5SSTR4SSTR2
SCHEMBL20206296 0.95 MC1R (0.56) MC4RMC1RIL23R
SCHEMBL20206282 0.94 MC4R (0.55) MC4RMC1RIL23R
SCHEMBL20363000 0.93 MC4R (0.55) MC4RMC1R
SCHEMBL21392332 0.93 MC4R (0.55) MC4RMC1R
SCHEMBL20362979 0.93 MC4R (0.55) MC4RMC1R
SCHEMBL21392401 0.90 MC4R (0.58) MC4RMC1RIL23R
SCHEMBL20206176 0.90 MC1R (0.53) MC4RMC1RIL23RREN

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2019183472-A1 MELANOCORTIN RECEPTOR-SPECIFIC PEPTIDE FORMULATIONS AND METHODS FOR GASTROINTESTINAL TRACT-SPECIFIC DELIVERY PALATIN TECHNOLOGIES, INC. (US) 2019-09-26 — — WO disclosed
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