Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.49 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | MMP9 | P14780 | 1/20 | 0.41 |
| ▸ | MMP8 | P22894 | 1/20 | 0.41 |
| ▸ | MMP14 | P50281 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | PLA2G2C | Q5R387 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13595807 | 0.86 | HSD17B10 (0.50) | ALDH1A1CYP3A4USP2LMNAHSD17B10 | |
| SCHEMBL1710091 | 0.84 | CYP3A4 (0.67) | ALDH1A1CYP3A4USP2LMNAHSD17B10 | |
| SCHEMBL20725831 | 0.84 | CYP3A4 (0.67) | ALDH1A1CYP3A4USP2LMNAHSD17B10 | |
| SCHEMBL19514984 | 0.83 | CYP3A4 (0.59) | ALDH1A1CYP3A4USP2LMNAHSD17B10 | |
| SCHEMBL25753062 | 0.82 | TSHR (0.56) | ALDH1A1CYP3A4USP2LMNAMMP9 | |
| SCHEMBL1839353 | 0.79 | CYP3A4 (0.71) | ALDH1A1CYP3A4LMNAHSD17B10MMP9 | |
| SCHEMBL3432858 | 0.79 | CYP3A4 (0.71) | ALDH1A1CYP3A4USP2LMNAHSD17B10 | |
| SCHEMBL3765751 | 0.79 | CYP3A4 (0.71) | ALDH1A1CYP3A4LMNAHSD17B10MMP9 | |
| SCHEMBL11905467 | 0.79 | CYP3A4 (0.71) | ALDH1A1CYP3A4LMNAHSD17B10MMP9 | |
| SCHEMBL13007628 | 0.79 | CYP3A4 (0.71) | ALDH1A1CYP3A4USP2LMNAHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3770256-A1 | ANTISENSE OLIGONUCLEOTIDE HAVING REDUCED TOXICITY | Tokyo Institute of Technology (JP) | 2021-01-27 | — | — | EP | disclosed |
| WO-2019182037-A1 | ANTISENSE OLIGONUCLEOTIDE HAVING REDUCED TOXICITY | 国立大学法人東京工業大学 | 2019-09-26 | — | — | WO | disclosed |