Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | BLM | P54132 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.30 |
| ▸ | PLK1 | P53350 | 1/20 | 0.30 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.30 |
| ▸ | PLK3 | Q9H4B4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2516619 | 0.71 | — | — | |
| SCHEMBL17895992 | 0.71 | SMN1; SMN2 (0.33) | KDM4EALDH1A1POLBHIF1A | |
| SCHEMBL24962376 | 0.69 | — | — | |
| SCHEMBL568791 | 0.69 | — | — | |
| SCHEMBL16322235 | 0.69 | — | — | |
| SCHEMBL14937452 | 0.69 | — | — | |
| SCHEMBL21397739 | 0.69 | POLB (0.33) | KDM4EALDH1A1POLBHIF1A | |
| SCHEMBL11967064 | 0.68 | HIF1A (0.32) | KDM4EALDH1A1HIF1A | |
| SCHEMBL21030220 | 0.68 | MAPT (0.35) | KDM4EALDH1A1BLMPOLB | |
| SCHEMBL17895792 | 0.67 | SMN1; SMN2 (0.33) | KDM4EALDH1A1POLBHIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019182925-A1 | OXADIAZOLE TRANSIENT RECEPTOR POTENTIAL CHANNEL INHIBITORS | GENENTECH, INC. (US) | 2019-09-26 | — | — | WO | disclosed |