Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.67 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.67 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8260642 | 0.80 | GAA (1.00) | GAATDP1CA1CA2CA9 | |
| SCHEMBL21384226 | 0.72 | GAA (0.44) | GAATDP1POLBCA12CA1 | |
| SCHEMBL2755792 | 0.70 | — | — | |
| SCHEMBL15038570 | 0.68 | — | — | |
| SCHEMBL11242820 | 0.67 | HRH3 (0.46) | GAATDP1HRH3 | |
| SCHEMBL12932817 | 0.65 | GAA (0.41) | GAATDP1 | |
| SCHEMBL20284268 | 0.64 | GAA (0.59) | GAATDP1 | |
| SCHEMBL12299952 | 0.64 | GAA (0.39) | GAATDP1 | |
| SCHEMBL21500442 | 0.63 | GAA (0.39) | GAATDP1 | |
| SCHEMBL1698550 | 0.63 | SMN1; SMN2 (0.41) | GAATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020198026-A1 | COMPOUNDS AND USES THEREOF | YUMANITY THERAPEUTICS, INC. (US) | 2020-10-01 | — | — | WO | disclosed |
| WO-2019183587-A1 | COMPOUNDS AND USES THEREOF | YUMANITY THERAPEUTICS, INC. (US) | 2019-09-26 | — | — | WO | disclosed |