Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 5/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | GCK | P35557 | 1/20 | 0.38 |
| ▸ | DEGS1 | O15121 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.38 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21394711 | 0.91 | NPC1 (0.44) | GRM5L3MBTL1SMN1; SMN2NPC1TSHR | |
| SCHEMBL29358350 | 0.91 | NPC1 (0.44) | GRM5L3MBTL1SMN1; SMN2NPC1TSHR | |
| SCHEMBL21395129 | 0.86 | GRM5 (0.40) | GRM5L3MBTL1SMN1; SMN2NPC1TSHR | |
| SCHEMBL21394687 | 0.86 | NPC1 (0.43) | GRM5SMN1; SMN2NPC1TSHRRAB9A | |
| SCHEMBL21394572 | 0.86 | TSHR (0.44) | GRM5L3MBTL1SMN1; SMN2NPC1TSHR | |
| SCHEMBL29357109 | 0.86 | TSHR (0.44) | GRM5L3MBTL1SMN1; SMN2NPC1TSHR | |
| SCHEMBL21395189 | 0.84 | ABCB1 (0.45) | GRM5SMN1; SMN2NPC1RAB9AABCB1 | |
| SCHEMBL21394883 | 0.83 | MEN1 (0.47) | SMN1; SMN2NPC1TSHRRAB9A | |
| SCHEMBL29356651 | 0.83 | MEN1 (0.47) | SMN1; SMN2NPC1TSHRRAB9A | |
| SCHEMBL21394747 | 0.82 | AHR (0.38) | GRM5GCKSMN1; SMN2NPC1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019183587-A1 | COMPOUNDS AND USES THEREOF | YUMANITY THERAPEUTICS, INC. (US) | 2019-09-26 | — | — | WO | disclosed |