SCHEMBL2139645

SCHEMBL2139645

CC=C(CC(C)O)C(=O)O

nearest known ligand 0.56

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
GRIK1 P39086 9/20 0.56
GRIK2 Q13002 5/20 0.56
GRIA2 P42262 2/20 0.41
GRIA4 P48058 2/20 0.41
GRIK3 Q13003 2/20 0.41
GRIK5 Q16478 2/20 0.41
GRIA1 P42261 1/20 0.41
TP53 P04637 1/20 0.35
SLC22A6 Q4U2R8 1/20 0.32
KDM4E B2RXH2 1/20 0.31
TSHR P16473 1/20 0.31
ALDH1A1 P00352 1/20 0.31
TDP1 Q9NUW8 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2139638 1.00 GRIK1 (0.56) GRIK1GRIK2GRIA2GRIA4GRIK3
SCHEMBL5707879 0.83 GRIK1 (0.39) GRIK1GRIK2GRIA2GRIA4GRIK3
SCHEMBL10450348 0.82 GRIK1 (0.58) GRIK1GRIK2GRIA2GRIA4GRIK3
SCHEMBL3620136 0.82 GRIK1 (0.58) GRIK1GRIK2GRIA2GRIA4GRIK3
SCHEMBL8377796 0.82 GRIK1 (0.58) GRIK1GRIK2GRIA2GRIA4GRIK3
SCHEMBL320056 0.81 GRIK1 (0.38) GRIK1GRIK2GRIA2GRIA4GRIK3
SCHEMBL10937503 0.81 KDM4E (0.48) GRIK1GRIK2GRIA2GRIA4GRIK3
SCHEMBL10937515 0.81 KDM4E (0.48) GRIK1GRIK2GRIA2GRIA4GRIK3
SCHEMBL11802504 0.81 KDM4E (0.48) GRIK1GRIK2GRIA2GRIA4GRIK3
SCHEMBL10942638 0.79 GRIK1 (0.52) GRIK1GRIK2GRIA2GRIA4GRIK3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2601229-B1 GRAFT COPOLYMERS OF POLYFARNESENES WITH CONDENSATION POLYMERS AMYRIS INC (US) 2013-10-16 EP claimed
EP-2812392-B1 BEARING SURFACE MIXTURE CONTAINING MICRO-GEL FOR WINTER TYRES ARLANXEO DEUTSCHLAND GMBH (DE) 2018-08-22 EP disclosed
CN-105008478-B Double-sided adhesive sheet 琳得科株式会社 2018-06-05 CN disclosed
EP-2812392-A1 MICROGEL-CONTAINING TREAD MIXTURE FOR WINTER TYRES Lanxess Deutschland GmbH (DE) 2014-12-17 EP disclosed
WO-2013117762-A1 MICROGEL-CONTAINING TREAD MIXTURE FOR WINTER TYRES LANXESS DEUTSCHLAND GMBH (DE) 2013-08-15 WO disclosed
US-20110006245-A1 POLYMER COATED INORGANIC FINE PARTICLE AND METHOD FOR PREPARING THE SAME TAMAGAWA SEIKI CO., LTD. (JP) 2011-01-13 US disclosed
EP-2221327-A1 POLYMER-COATED FINE INORGANIC PARTICLE AND PROCESS FOR PRODUCING THE SAME Handa, Hiroshi (JP) 2010-08-25 EP disclosed
WO-2001044333-A1 THERMOSETTING RESIN OBTAINED BY REACTION OF A TRIAZINE COMPOUND WITH AN ALDEHYDE AND AN ACTIVATED OLEFINIC COMPOUND DSM N.V. (NL) 2001-06-21 WO disclosed
EP-0632127-A1 Use of colostrum or mother's milk to inhibit the accumulation of proteins on the surface of synthetic polymers used in contact with biological systems; application in the care of contact lenses ESSILOR INTERNATIONAL COMPAGNIE GENERALE D'OPTIQUE (FR) 1995-01-04 EP disclosed
US-4323363-A DISPERSE DYE USED ON POLYESTERS MIXED WITH CELLULOSE CASSELLA AKTIENGESELLSCHAFT (DE) 1982-04-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110006245-A1 POLYMER COATED INORGANIC FINE PARTICLE AND METHOD FOR PREPARING THE SAME CYP4F12, CYP2F1, CYP4F3 GRIK1 2424/4885GRIK2 1446/4885GRIA2 465/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.