Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.55 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | G6PD | P11413 | 1/20 | 0.41 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.41 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.41 |
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 5/20 | 0.39 |
| ▸ | HTT | P42858 | 4/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.38 |
| ▸ | NPY1R | P25929 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5005525 | 1.00 | KMT2A (0.55) | KMT2ATRPV1MEN1G6PDCACNA1B | |
| SCHEMBL5005524 | 1.00 | KMT2A (0.55) | KMT2ATRPV1MEN1G6PDCACNA1B | |
| SCHEMBL2087130 | 0.89 | KMT2A (0.43) | KMT2AMEN1ALDH1A1KDM4EGAA | |
| SCHEMBL4920373 | 0.89 | KMT2A (0.43) | KMT2AMEN1ALDH1A1KDM4EGAA | |
| SCHEMBL12793870 | 0.89 | KMT2A (0.43) | KMT2AMEN1ALDH1A1KDM4EGAA | |
| SCHEMBL7758055 | 0.87 | KMT2A (0.47) | KMT2ATRPV1MEN1ALDH1A1GAA | |
| SCHEMBL7758060 | 0.87 | KMT2A (0.47) | KMT2ATRPV1MEN1ALDH1A1GAA | |
| SCHEMBL16014631 | 0.87 | DHODH (0.41) | KMT2AMEN1ALDH1A1KDM4EMAPT | |
| SCHEMBL16014632 | 0.87 | DHODH (0.41) | KMT2AMEN1ALDH1A1KDM4EMAPT | |
| SCHEMBL23576281 | 0.85 | KMT2A (0.43) | KMT2AMEN1CACNA1BAPBA1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019179362-A1 | AMIDINE AND GUANIDINE DERIVATIVES, PREPARATION METHOD THEREFOR AND MEDICAL USES THEREOF | 四川科伦博泰生物医药股份有限公司 | 2019-09-26 | — | — | WO | disclosed |