Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CKS1B | P61024 | 1/20 | 0.53 |
| ▸ | SKP1 | P63208 | 1/20 | 0.53 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.53 |
| ▸ | SUV39H2 | Q9H5I1 | 7/20 | 0.47 |
| ▸ | CHRNB2 | P17787 | 3/20 | 0.46 |
| ▸ | CHRNA4 | P43681 | 3/20 | 0.46 |
| ▸ | CHRNB4 | P30926 | 2/20 | 0.46 |
| ▸ | CHRNA3 | P32297 | 2/20 | 0.46 |
| ▸ | CNR1 | P21554 | 1/20 | 0.45 |
| ▸ | CNR2 | P34972 | 1/20 | 0.45 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.44 |
| ▸ | MET | P08581 | 1/20 | 0.44 |
| ▸ | CFTR | P13569 | 1/20 | 0.42 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.42 |
| ▸ | DRD2 | P14416 | 1/20 | 0.42 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.42 |
| ▸ | CTSK | P43235 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4760818 | 0.87 | CKS1B (0.56) | CKS1BSKP1SKP2SUV39H2CNR1 | |
| SCHEMBL4827769 | 0.86 | CKS1B (0.55) | CKS1BSKP1SKP2SUV39H2CNR1 | |
| SCHEMBL15252426 | 0.85 | CKS1B (0.54) | CKS1BSKP1SKP2SUV39H2CNR1 | |
| SCHEMBL21698701 | 0.84 | CKS1B (0.53) | CKS1BSKP1SKP2SUV39H2CNR1 | |
| SCHEMBL16691339 | 0.83 | SUV39H2 (0.51) | CKS1BSKP1SKP2SUV39H2CFTR | |
| SCHEMBL18661974 | 0.83 | CKS1B (0.50) | CKS1BSKP1SKP2SUV39H2CNR1 | |
| SCHEMBL17557723 | 0.82 | MAPT (0.56) | CKS1BSKP1SKP2SUV39H2GPR119 | |
| SCHEMBL15252451 | 0.81 | MAPT (0.51) | CKS1BSKP1SKP2SUV39H2CHRNB2 | |
| SCHEMBL18661944 | 0.81 | CKS1B (0.50) | CKS1BSKP1SKP2SUV39H2CNR1 | |
| SCHEMBL7487866 | 0.81 | CKS1B (0.50) | CKS1BSKP1SKP2SUV39H2CHRNB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019179362-A1 | AMIDINE AND GUANIDINE DERIVATIVES, PREPARATION METHOD THEREFOR AND MEDICAL USES THEREOF | 四川科伦博泰生物医药股份有限公司 | 2019-09-26 | — | — | WO | disclosed |