Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | UBE2T | Q9NPD8 | 1/20 | 0.41 |
| ▸ | ASIC3 | Q9UHC3 | 1/20 | 0.41 |
| ▸ | UBE2M | P61081 | 6/20 | 0.40 |
| ▸ | DCUN1D1 | Q96GG9 | 6/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | TP53 | P04637 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2592039 | 0.77 | KMT2A (0.56) | KMT2AMEN1SMN1; SMN2CYP1A2CYP3A4 | |
| SCHEMBL9533470 | 0.75 | KMT2A (0.77) | KMT2AMEN1SMN1; SMN2CYP1A2CYP3A4 | |
| SCHEMBL1744058 | 0.73 | KMT2A (0.73) | KMT2AMEN1SMN1; SMN2CYP1A2CYP3A4 | |
| SCHEMBL5637621 | 0.73 | KMT2A (0.73) | KMT2AMEN1SMN1; SMN2CYP1A2CYP3A4 | |
| SCHEMBL816962 | 0.71 | KMT2A (0.71) | KMT2AMEN1SMN1; SMN2CYP1A2CYP3A4 | |
| SCHEMBL28919884 | 0.71 | KMT2A (0.71) | KMT2AMEN1SMN1; SMN2CYP1A2CYP3A4 | |
| SCHEMBL30702394 | 0.71 | KMT2A (0.71) | KMT2AMEN1SMN1; SMN2CYP1A2CYP3A4 | |
| SCHEMBL22084261 | 0.70 | MEN1 (0.56) | KMT2AMEN1SMN1; SMN2CYP1A2CYP3A4 | |
| SCHEMBL28708297 | 0.70 | MEN1 (0.56) | KMT2AMEN1SMN1; SMN2CYP1A2CYP3A4 | |
| SCHEMBL1588423 | 0.70 | KMT2A (0.69) | KMT2AMEN1SMN1; SMN2CYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3755383-B1 | TRICARBONYL COMPLEXES OF TRANSITION METALS WITH BENZO-HETEROCYCLIC DERIVATIVES OF THE CYCLOPENTADIENYL ANION | NATIONAL CENTER FOR SCIENT RESEARCH DEMOKRITOS (GR) | 2021-08-18 | — | — | EP | disclosed |
| WO-2019180200-A1 | TRICARBONYL COMPLEXES OF TRANSITION METALS WITH BENZO-HETEROCYCLIC DERIVATIVES OF THE CYCLOPENTADIENYL ANION | NATIONAL CENTRE FOR SCIENTIFIC RESEARCH "DEMOKRITOS" (GR) | 2019-09-26 | — | — | WO | disclosed |