⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7049400 | 0.77 | — | — | |
| SCHEMBL19790311 | 0.76 | — | — | |
| SCHEMBL2139141 | 0.73 | — | — | |
| SCHEMBL25208568 | 0.65 | — | — | |
| SCHEMBL6483532 | 0.59 | — | — | |
| SCHEMBL5693075 | 0.59 | — | — | |
| SCHEMBL4558690 | 0.59 | — | — | |
| Ammonia Solution, Strong SCHEMBL1894154 | 0.58 | — | — | |
| SCHEMBL37871 | 0.58 | — | — | |
| SCHEMBL4701716 | 0.57 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8552000-B2 | Therapeutic agent for senile dementia | DAINIPPON SUMITOMO PHARMA CO., LTD. (JP) | 2013-10-08 | — | — | US | disclosed |
| US-20120165341-A1 | THERAPEUTIC AGENT FOR SENILE DEMENTIA | DAINIPPON SUMITOMO PHARMA CO., LTD. | 2012-06-28 | — | — | US | disclosed |
| US-8148379-B2 | Use of lurasidone (N-[(1R,2R)-2-[4-(1,2-benzisothiazol-3-yl)-1-piperazinyl-methyl]-1-cyclohexylmethyl]-2,3-bicycl[2.2.1]heptanedicarboxyimide) | DAINIPPON SUMITOMO PHARMA CO., LTD. (JP) | 2012-04-03 | — | — | US | disclosed |
| US-20080255148-A1 | Use of lurasidone (N-[(1R,2R)-2-[4-(1,2-benzisothiazol-3-yl)-1-piperazinyl-methyl]-1-cyclohexylmethyl]-2,3-bicycl[2.2.1]heptanedicarboxyimide) | DAINPPON SUMITOMO PHARMA CO., LTD. (JP) | 2008-10-16 | — | — | US | disclosed |
| US-20060142276-A1 | Therapeutic agent for senile dementia | DAINIPPON SUMITOMO PHARMA CO. LTD. (JP) | 2006-06-29 | — | — | US | disclosed |
| EP-1637530-A1 | THERAPEUTIC AGENT FOR SENILE DEMENTIA | Dainippon Sumitomo Pharma Co., Ltd. (JP) | 2006-03-22 | — | — | EP | disclosed |
| EP-0464846-B1 | Imide derivatives, and their production and use | SUMITOMO PHARMA (JP) | 1998-04-22 | — | — | EP | disclosed |
| EP-0464846-A1 | Imide derivatives, and their production and use | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1992-01-08 | — | — | EP | disclosed |