Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.57 |
| ▸ | MEN1 | O00255 | 1/20 | 0.57 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.57 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.57 |
| ▸ | GAA | P10253 | 2/20 | 0.56 |
| ▸ | HPGD | P15428 | 2/20 | 0.56 |
| ▸ | CRHBP | P24387 | 1/20 | 0.55 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.54 |
| ▸ | ATM | Q13315 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.53 |
| ▸ | CNR2 | P34972 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | RAB9A | P51151 | 1/20 | 0.53 |
| ▸ | CNR1 | P21554 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.53 |
| ▸ | PKM | P14618 | 1/20 | 0.53 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phenaceturic Acid SCHEMBL196523 | 0.84 | ATM (0.62) | KMT2AMEN1HDAC8HDAC6GAA | |
| Phenaceturic Acid SCHEMBL14126285 | 0.84 | ATM (0.62) | KMT2AMEN1HDAC8HDAC6GAA | |
| SCHEMBL11034177 | 0.84 | HDAC8 (0.65) | KMT2AMEN1HDAC8HDAC6GAA | |
| SCHEMBL1454495 | 0.82 | MEN1 (0.63) | KMT2AMEN1HDAC8HDAC6GAA | |
| SCHEMBL11288698 | 0.81 | ATM (0.59) | KMT2AMEN1HDAC8HDAC6GAA | |
| SCHEMBL7769256 | 0.81 | KMT2A (0.57) | KMT2AMEN1HDAC8HDAC6GAA | |
| SCHEMBL5102819 | 0.81 | KMT2A (0.57) | KMT2AMEN1HDAC8HDAC6GAA | |
| SCHEMBL7769258 | 0.81 | KMT2A (0.57) | KMT2AMEN1HDAC8HDAC6GAA | |
| SCHEMBL22559999 | 0.80 | MEN1 (0.61) | KMT2AMEN1HDAC8HDAC6GAA | |
| SCHEMBL5848410 | 0.79 | MAPT (0.56) | KMT2AMEN1HDAC8HDAC6GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019182942-A1 | TYROSINE-SPECIFIC FUNCTIONALIZED INSULIN AND INSULIN ANALOGS | MERCK SHARP & DOHME CORP. (US) | 2019-09-26 | — | — | WO | disclosed |