SCHEMBL214008

SCHEMBL214008

Nc1ccc(OCC(=O)O)c(N)c1

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTGDR2 Q9Y5Y4 8/20 0.64
MAPT P10636 2/20 0.51
USP2 O75604 2/20 0.51
POLB P06746 2/20 0.51
KDM4E B2RXH2 1/20 0.51
MEN1 O00255 1/20 0.51
ALDH1A1 P00352 1/20 0.51
TP53 P04637 1/20 0.51
GAA P10253 1/20 0.51
CASP1 P29466 1/20 0.51
HTT P42858 1/20 0.51
CASP7 P55210 1/20 0.51
KMT2A Q03164 1/20 0.51
ATM Q13315 1/20 0.51
TDP1 Q9NUW8 2/20 0.50
PKM P14618 1/20 0.47
TSHR P16473 1/20 0.45
SMN1; SMN2 Q16637 2/20 0.45
NPC1 O15118 1/20 0.45
RAB9A P51151 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29835046 1.00 PTGDR2 (0.64) PTGDR2MAPTUSP2POLBKDM4E
Hydrochloric Acid SCHEMBL28833707 0.98 PTGDR2 (0.62) PTGDR2MAPTUSP2POLBKDM4E
SCHEMBL8905331 0.87 PTGDR2 (0.66) PTGDR2MAPTPOLBMEN1ALDH1A1
SCHEMBL10595469 0.85 PTGDR2 (0.59) PTGDR2MAPTUSP2POLBKDM4E
Hydrochloric Acid SCHEMBL8484286 0.85 PTGDR2 (0.64) PTGDR2MAPTPOLBKDM4EMEN1
SCHEMBL15933189 0.85 KDM4E (0.51) PTGDR2MAPTUSP2POLBKDM4E
Hydrochloric Acid SCHEMBL9003495 0.84 PTGDR2 (0.56) PTGDR2MAPTUSP2POLBKDM4E
SCHEMBL10816768 0.82 PTGDR2 (0.60) PTGDR2POLBKDM4ETDP1TSHR
SCHEMBL1028925 0.82 PTGDR2 (0.60) PTGDR2MAPTPOLBMEN1KMT2A
SCHEMBL10791590 0.82 USP2 (0.57) PTGDR2MAPTUSP2POLBKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1220 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024089704-A1 A COMPOSITION FOR IMPROVING EFFECTIVENESS OF DYE PRECURSORS FOR CHANGE OF COLOUR OF HAIR CAVINKARE PVT.LTD. (IN) 2024-05-02 WO claimed
EP-3096735-A1 GRADUAL HAIRCOLOR COMPOSITIONS AND METHODS OF USING THE SAME Combe International Ltd. (US) 2016-11-30 EP claimed
CN-105916482-A Gradual hair color compositions and methods of use thereof 酷姆国际公司 2016-08-31 CN claimed
EP-1674075-B1 Hair colouring process comprising a cleaning step ORÉAL L (FR) 2016-07-20 EP claimed
WO-2015112789-A1 GRADUAL HAIRCOLOR COMPOSITIONS AND METHODS OF USING THE SAME COMBE INTERNATIONAL LTD. (US) 2015-07-30 WO claimed
CN-103249455-A Process for dyeing keratin fibres using hydroxybenzaldehyde derivatives, oxidizing agents and alkalinizing agents in the presence of heat OREAL 2013-08-14 CN claimed
JP-4785024-B2 2011-10-05 JP claimed
EP-1494995-B1 3-AMINOPHENOL DERIVATIVES SUBSTITUTED IN THE 2-POSITION, AND DYES CONTAINING THESE COMPOUNDS PROCTER & GAMBLE (US) 2010-09-22 EP claimed
US-RE41549-E1 Dyes for keratin fibers, the dyes containing n-benzyl-p-phenylenediamine derivatives and novel n-benzyl-p-phenylenediamine derivatives WELLA AG (DE) 2010-08-24 US claimed
EP-0634162-B2 Dyeing composition for keratinous fibers containing a para-aminophenol, a meta-aminophenol and a metaphenylendiamine OREAL (FR) 2009-07-22 EP claimed
EP-1116711-A2 2-aminoalkyl-1,4-diaminobenzene derivatives and dye composition containing these compounds Wella Aktiengesellschaft (DE) 2001-07-18 EP claimed
US-6132475-A FOR OXIDATION DYEING OF KERATIN FIBERS; INCLUDES COUPLER AND DEVELOPER, IN WHICH THE DEVELOPER IS A SUBSTITUTED 2-(FURYL, THIENYL, PYRROLYL, OR SELENOPHENE) P-DIAMINOBENZENE DERIVATIVE OF GIVEN FORMULA; COLORFASTNESS, WASHFASTNESS WELLA AKTIENGESELLSCHAFT (DE) 2000-10-17 US claimed
US-6042620-A FOR DYEING KERATIN FIBERS SUCH AS HAIR WELLA AG (DE) 2000-03-28 US claimed
EP-0963982-A2 New diaminobenzene derivatives and these componends containing colouring agents Wella Aktiengesellschaft (DE) 1999-12-15 EP claimed
EP-0943614-A2 Dyeing agents comprising diaminobenzene derivatives and the diaminobenzene derivatives Wella Aktiengesellschaft (DE) 1999-09-22 EP claimed
EP-0634162-B1 Dyeing composition for keratinous fibers containing a para-aminophenol, a meta-aminophenol and a metaphenylendiamine OREAL (FR) 1998-11-04 EP claimed
EP-0605320-B1 Dye composition for keratinic fibres based on paraphenylenediamine, metaphenylenediamines and benzimidazol derivates, and the dyeing process using same OREAL (FR) 1997-04-09 EP claimed
US-5578087-A Dyeing compositions for keratinous fibres based on para-phenylene-diamines, meta-phenylenediamine and benzimidazole derivatives, and dyeing process employing them L'OREAL (FR) 1996-11-26 US claimed
US-4904275-A OXIDIZER L'OREAL (FR) 1990-02-27 US claimed
US-4684371-A Oxidation hair dyes comprising m-phenylenediamine derivatives as coupling components HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 1987-08-04 US claimed