SCHEMBL21400933

SCHEMBL21400933

C=C(C)C(=O)OCCc1cc(-c2ccc(-c3ccc(C4CCC(CCCCC)CC4)cc3)cc2)ccc1OCCC(CO)(CO)CCCC

nearest known ligand 0.36

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
DGAT1 O75907 1/20 0.32
CYP2C9 P11712 1/20 0.31
TSHR P16473 2/20 0.31
PTPN11 Q06124 1/20 0.31
PPARD Q03181 1/20 0.31
PPARA Q07869 1/20 0.31
RAB9A P51151 1/20 0.30
ALDH1A1 P00352 1/20 0.30
LMNA P02545 1/20 0.30
MAPT P10636 1/20 0.30
P2RY14 Q15391 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18646681 0.96
SCHEMBL21232272 0.95 PPARD (0.30) PPARD
SCHEMBL18646686 0.93
SCHEMBL18645612 0.92
SCHEMBL21232349 0.92 PPARD (0.30) PPARD
SCHEMBL20171760 0.92 PPARG (0.32) TSHRPPARDPPARA
SCHEMBL21115409 0.91
SCHEMBL21231998 0.91 TSHR (0.30) TSHR
SCHEMBL19007877 0.91 TSHR (0.34) DGAT1CYP2C9TSHRPTPN11PPARD
SCHEMBL18646389 0.91

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 77 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12043781-B2 Liquid-crystalline medium MERCK PATENT GMBH (DE) 2024-07-23 US disclosed
US-12043781-B2 Liquid-crystalline medium MERCK PATENT GMBH (DE) 2024-07-23 US disclosed
EP-3924447-B1 POLYMERISABLE COMPOUNDS AND THE USE THEREOF IN LIQUID-CRYSTAL DISPLAYS MERCK PATENT GMBH (DE) 2024-01-24 EP disclosed
EP-4306614-A1 LIQUID-CRYSTALLINE MEDIUM Merck Patent GmbH (DE) 2024-01-17 EP disclosed
US-11802243-B2 Liquid-crystal medium MERCK PATENT GMBH (DE) 2023-10-31 US disclosed
US-11802243-B2 Liquid-crystal medium MERCK PATENT GMBH (DE) 2023-10-31 US disclosed
US-20230340328-A1 LIQUID-CRYSTALLINE MEDIUM MERCK PATENT GMBH (DE) 2023-10-26 US disclosed
US-20230340328-A1 LIQUID-CRYSTALLINE MEDIUM MERCK PATENT GMBH (DE) 2023-10-26 US disclosed
WO-2023198669-A1 LIQUID-CRYSTALLINE MEDIUM MERCK PATENT GMBH (DE) 2023-10-19 WO disclosed
WO-2023198671-A1 LIQUID-CRYSTALLINE MEDIUM MERCK PATENT GMBH (DE) 2023-10-19 WO disclosed
US-20210024826-A1 LIQUID-CRYSTAL DISPLAY MERCK PATENT GMBH (DE) 2021-01-28 US disclosed
US-20200407640-A1 LC MEDIUM MERCK PATENT GMBH (DE) 2020-12-31 US disclosed
EP-3757192-A1 LIQUID CRYSTALLINE MEDIUM Merck Patent GmbH (DE) 2020-12-30 EP disclosed
US-20200339882-A1 LIQUID-CRYSTAL MEDIUM MERCK PATENT GMBH (DE) 2020-10-29 US disclosed
EP-3730591-A1 LIQUID-CRYSTAL MEDIUM Merck Patent GmbH (DE) 2020-10-28 EP disclosed
EP-3666853-A1 LIQUID-CRYSTAL MEDIUM Merck Patent GmbH (DE) 2020-06-17 EP disclosed
US-20200181493-A1 LIQUID-CRYSTAL MEDIUM MERCK PATENT GMBH (DE) 2020-06-11 US disclosed
US-20200040257-A1 LIQUID-CRYSTAL MEDIUM MERCK PATENT GMBH (DE) 2020-02-06 US disclosed
EP-3604481-A1 LIQUID-CRYSTAL MEDIUM Merck Patent GmbH (DE) 2020-02-05 EP disclosed
WO-2019180060-A1 LIQUID-CHRYSTAL DISPLAY MERCK PATENT GMBH (DE) 2019-09-26 WO disclosed