SCHEMBL21400965

SCHEMBL21400965

C1=CNC2NCCCC2=C1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17734088 0.88
SCHEMBL2152496 0.65
SCHEMBL21402003 0.64
SCHEMBL19807105 0.64 CHRM5 (0.31)
SCHEMBL6557702 0.64
SCHEMBL20418303 0.64 KDM1A (0.33)
SCHEMBL7574559 0.62
Piperazine SCHEMBL7170530 0.58
Hydrochloric Acid SCHEMBL4401072 0.58
Hydrochloric Acid SCHEMBL1275326 0.57

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4252856-A2 NOVEL QUINAZOLINONES THAT INHIBIT THE FORMATION OF TAU OLIGOMERS AND THEIR METHOD OF USE Oligomerix, Inc. (US) 2023-10-04 EP disclosed
WO-2019182944-A1 NOVEL KINASE INHIBITORS EXHIBITING ANTI-CANCER ACTIVITY AND THEIR METHOD OF USE ALLCRON PHARMA INC. (US) 2019-09-26 WO disclosed