SCHEMBL2140496

SCHEMBL2140496

CC(C)(c1ccccc1)c1c(OP(=O)(O)O)ccc(-c2ccccc2)c1-c1ccccc1

nearest known ligand 0.37

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.37
KDM4E B2RXH2 1/20 0.37
USP2 O75604 1/20 0.37
HPGD P15428 1/20 0.37
PDE3A Q14432 1/20 0.37
HSD17B10 Q99714 1/20 0.37
GPR84 Q9NQS5 1/20 0.37
INPPL1 O15357 5/20 0.36
INPP5A Q14642 4/20 0.36
SRC P12931 2/20 0.36
AKT1 P31749 1/20 0.36
CNR1 P21554 3/20 0.35
CNR2 P34972 3/20 0.35
PTPN5 P54829 4/20 0.34
INPP5B P32019 2/20 0.34
PTPN1 P18031 2/20 0.33
ESR1 P03372 1/20 0.32
CYP3A4 P08684 1/20 0.32
ESR2 Q92731 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11111474 0.88 KDM4E (0.40) ALDH1A1KDM4EUSP2HPGDPDE3A
SCHEMBL9579240 0.86 PTPN5 (0.39) ALDH1A1KDM4EUSP2HPGDPDE3A
SCHEMBL3287701 0.79 SRC (0.41) ALDH1A1KDM4EUSP2HPGDPDE3A
SCHEMBL30473235 0.78 KDM4E (0.46) ALDH1A1KDM4EUSP2HPGDPDE3A
SCHEMBL7642864 0.78 KDM4E (0.46) ALDH1A1KDM4EUSP2HPGDPDE3A
SCHEMBL8596411 0.76 INPPL1 (0.46) ALDH1A1KDM4EUSP2HPGDPDE3A
SCHEMBL11073854 0.75 KDM4E (0.42) ALDH1A1KDM4EUSP2HPGDPDE3A
SCHEMBL985289 0.74 CNR1 (0.48) ALDH1A1HPGDHSD17B10CNR1CNR2
SCHEMBL30353459 0.74 KDM4E (0.45) ALDH1A1KDM4EUSP2HPGDPDE3A
SCHEMBL184529 0.74 KDM4E (0.45) ALDH1A1KDM4EUSP2HPGDPDE3A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3380560-B1 POLYCARBONATE-ASA BLENDS WITH ANTISTATIC PROPERTIES USING SULFONATED ALKANES INEOS STYROLUTION GROUP GMBH (DE) 2019-08-14 EP disclosed
US-20180346715-A1 POLYCARBONATE-ASA BLENDS WITH ANTISTATIC PROPERTIES USING SULFONATED ALKANES HSBC CORPORATE TRUSTEE COMPANY (UK) LIMITED (GB) 2018-12-06 US disclosed
EP-3380560-A1 POLYCARBONATE-ASA BLENDS WITH ANTISTATIC PROPERTIES USING SULFONATED ALKANES INEOS Styrolution Group GmbH (DE) 2018-10-03 EP disclosed
WO-2017089547-A1 POLYCARBONATE-ASA BLENDS WITH ANTISTATIC PROPERTIES USING SULFONATED ALKANES INEOS STYROLUTION GROUP GMBH (DE) 2017-06-01 WO disclosed
US-20150065622-A1 STABILIZED POLYCARBONATE/ACRYLONITRILE/STYRENE/ACRYLIC ESTER MOULDING COMPOUNDS Styrolution GmbH (DE) 2015-03-05 US disclosed
US-7863377-B2 Thermoplastic molding materials based on polyesters and styrene copolymers BASF AG (DE) 2011-01-04 US disclosed
US-7265172-B2 Polycarbonate styrene copolymer blends with improved properties BASF AKTIENGESELLSCHAFT (DE) 2007-09-04 US disclosed
US-20050159546-A1 Polycarbonate styrene copolymer blends with improved properties BASF AKTIENGESELLSCHAFT (DE) 2005-07-21 US disclosed
US-5272193-A Thermoplastic polycarbonate moulding compounds with flame-resistant properties BAYER AKTIENGESELLSCHAFT (DE) 1993-12-21 US disclosed
US-5157065-A Includes graft polymer, phosphate derivative, and antidripping agent BAYER AKTIENGESELLSCHAFT (DE) 1992-10-20 US disclosed