SCHEMBL21408387

SCHEMBL21408387

Cc1cc(O)c(C(=O)O)c(C)c1C(=O)O

nearest known ligand 0.63

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 7/20 0.63
ACHE P22303 2/20 0.63
MAPT P10636 3/20 0.53
MAPK1 P28482 3/20 0.47
ALDH1A1 P00352 3/20 0.47
KMT2A Q03164 3/20 0.47
HPGD P15428 3/20 0.47
MEN1 O00255 2/20 0.47
ALOX15 P16050 1/20 0.47
HSD17B10 Q99714 1/20 0.47
LDHA P00338 2/20 0.47
LDHB P07195 2/20 0.47
POLB P06746 3/20 0.46
KDM4E B2RXH2 1/20 0.46
GAA P10253 1/20 0.46
G6PD P11413 1/20 0.46
RECQL P46063 1/20 0.46
MCL1 Q07820 1/20 0.46
SMN1; SMN2 Q16637 2/20 0.44
TDP1 Q9NUW8 2/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8830347 0.86 CYP3A4 (0.57) CYP3A4ACHEMAPTMAPK1ALDH1A1
SCHEMBL28669355 0.86 CYP3A4 (0.57) CYP3A4ACHEMAPTMAPK1ALDH1A1
SCHEMBL8106142 0.85 CYP3A4 (0.54) CYP3A4ACHEMAPTMAPK1ALDH1A1
SCHEMBL9007037 0.84 CYP3A4 (0.55) CYP3A4ACHEMAPTMAPK1ALDH1A1
SCHEMBL27718325 0.84 CYP3A4 (0.65) CYP3A4ACHEMAPTMAPK1ALDH1A1
Hydrochloric Acid SCHEMBL5037307 0.83 CYP3A4 (0.52) CYP3A4ACHEMAPTMAPK1ALDH1A1
Hydrochloric Acid SCHEMBL5042476 0.83 CYP3A4 (0.52) CYP3A4ACHEMAPTMAPK1ALDH1A1
SCHEMBL2977807 0.82 CYP3A4 (0.57) CYP3A4ACHEMAPTMAPK1ALDH1A1
SCHEMBL22534121 0.82 CYP3A4 (0.57) CYP3A4ACHEMAPTMAPK1ALDH1A1
SCHEMBL10150815 0.81 CYP3A4 (0.52) CYP3A4ACHEMAPTMAPK1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2019185586-A1 LIGANDS FOR ENHANCED IMAGING AND DRUG DELIVERY TO NEUROBLASTOMA CELLS UNIVERSIDAD COMPLUTENSE DE MADRID (ES) 2019-10-03 WO disclosed