Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA4 | P22748 | 3/20 | 0.35 |
| ▸ | CA1 | P00915 | 2/20 | 0.34 |
| ▸ | CA5A | P35218 | 2/20 | 0.34 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28664668 | 0.84 | CA4 (0.39) | CA4CA1CA5ACA5B | |
| SCHEMBL4297049 | 0.79 | CA4 (0.39) | CA4 | |
| SCHEMBL1890700 | 0.79 | FOLH1 (0.32) | — | |
| SCHEMBL771738 | 0.79 | CA4 (0.39) | CA4 | |
| SCHEMBL771739 | 0.79 | CA4 (0.39) | CA4 | |
| Aminocarbonyl Dihydrogen Phosphate SCHEMBL21410683 | 0.77 | CA4 (0.50) | CA4CA1CA5ACA5B | |
| SCHEMBL1890693 | 0.77 | FOLH1 (0.35) | — | |
| SCHEMBL28006119 | 0.77 | CA4 (0.38) | CA4 | |
| Phosphoramidic Acid SCHEMBL1691899 | 0.76 | FOLH1 (0.34) | — | |
| Phosphoramidic Acid SCHEMBL13280710 | 0.76 | FOLH1 (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021189018-A9 | METHODS OF TREATING VIRAL INFECTIONS USING INHIBITORS OF NUCLEOTIDE SYNTHESIS PATHWAYS | Clear Creek Bio, Inc. (US) | 2022-04-28 | — | — | WO | disclosed |
| EP-3773579-A1 | COMPOSITIONS AND METHODS FOR INHIBITING DIHYDROOROTATE DEHYDROGENASE | Clear Creek Bio, Inc. (US) | 2021-02-17 | — | — | EP | disclosed |
| WO-2019191032-A1 | COMPOSITIONS AND METHODS FOR INHIBITING DIHYDROOROTATE DEHYDROGENASE | Clear Creek Bio, Inc. (US) | 2019-10-03 | — | — | WO | disclosed |