⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13318957 | 1.00 | — | — | |
| SCHEMBL158491 | 1.00 | — | — | |
| SCHEMBL30562964 | 1.00 | — | — | |
| SCHEMBL2708260 | 1.00 | — | — | |
| SCHEMBL3696195 | 0.88 | SLC1A2 (0.62) | — | |
| SCHEMBL3696199 | 0.88 | SLC1A2 (0.62) | — | |
| SCHEMBL8530336 | 0.86 | SLC1A2 (0.60) | — | |
| SCHEMBL8126946 | 0.86 | SLC1A2 (0.60) | — | |
| SCHEMBL25662044 | 0.86 | SLC1A2 (0.60) | — | |
| SCHEMBL25660492 | 0.85 | SLC1A2 (0.58) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11339193-B2 | CDP protein secretion inhibitors | KEZAR LIFE SCIENCES (US) | 2022-05-24 | — | — | US | disclosed |
| US-11339193-B2 | CDP protein secretion inhibitors | KEZAR LIFE SCIENCES (US) | 2022-05-24 | — | — | US | disclosed |
| US-20210289794-A1 | COMPOSITIONS AND RELATED METHODS FOR AGRICULTURE | FLAGSHIP PIONEERING INNOVATIONS V, INC. | 2021-09-23 | — | — | US | disclosed |
| CN-112513065-A | CDP protein secretion inhibitors | 科智生命科学公司 | 2021-03-16 | — | — | CN | disclosed |
| EP-3774850-A1 | CDP PROTEIN SECRETION INHIBITORS | Kezar Life Sciences (US) | 2021-02-17 | — | — | EP | disclosed |
| US-20210017233-A1 | CDP PROTEIN SECRETION INHIBITORS | ENODIA THERAPEUTICS SAS (FR) | 2021-01-21 | — | — | US | disclosed |
| US-20210017233-A1 | CDP PROTEIN SECRETION INHIBITORS | ENODIA THERAPEUTICS SAS (FR) | 2021-01-21 | — | — | US | disclosed |
| WO-2019191527-A1 | CDP PROTEIN SECRETION INHIBITORS | KEZAR LIFE SCIENCES (US) | 2019-10-03 | — | — | WO | disclosed |
| WO-2019191527-A1 | CDP PROTEIN SECRETION INHIBITORS | KEZAR LIFE SCIENCES (US) | 2019-10-03 | — | — | WO | disclosed |