Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 9/20 | 0.62 |
| ▸ | PPARG | P37231 | 3/20 | 0.62 |
| ▸ | FABP2 | P12104 | 2/20 | 0.62 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.62 |
| ▸ | MAPT | P10636 | 3/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.56 |
| ▸ | USP2 | O75604 | 2/20 | 0.56 |
| ▸ | POLB | P06746 | 2/20 | 0.56 |
| ▸ | HTT | P42858 | 1/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.55 |
| ▸ | CNR1 | P21554 | 4/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.55 |
| ▸ | ABCB11 | O95342 | 2/20 | 0.55 |
| ▸ | TSHR | P16473 | 2/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4755781 | 0.90 | PPARA (0.66) | PPARAPPARGFABP2SLC22A12MAPT | |
| SCHEMBL22221502 | 0.86 | PPARA (0.58) | PPARAPPARGFABP2SLC22A12MAPT | |
| SCHEMBL15682174 | 0.85 | PPARA (0.56) | PPARAPPARGFABP2SLC22A12MAPT | |
| SCHEMBL22221670 | 0.84 | PPARA (0.62) | PPARAPPARGFABP2SLC22A12MAPT | |
| SCHEMBL21413781 | 0.84 | PPARA (0.74) | PPARAPPARGFABP2MAPTSMN1; SMN2 | |
| SCHEMBL15682182 | 0.83 | ELANE (0.55) | PPARAPPARGFABP2SLC22A12MAPT | |
| SCHEMBL1584395 | 0.83 | PPARA (0.60) | PPARAPPARGFABP2SLC22A12MAPT | |
| SCHEMBL11160679 | 0.82 | PPARA (0.56) | PPARAPPARGFABP2SLC22A12MAPT | |
| SCHEMBL22221663 | 0.82 | PPARA (0.59) | PPARAPPARGFABP2SLC22A12MAPT | |
| SCHEMBL22221473 | 0.82 | PPARA (0.64) | PPARAPPARGFABP2SLC22A12MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10428013-B2 | Amide compound, preparation method and uses thereof | SHANGHAI INSTITUTE OF PHAMACEUTICAL INDUSTRY (CN) | 2019-10-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10428013-B2 | Amide compound, preparation method and uses thereof | F12, NR1H3, F2 | PPARA 185/4885PPARG 171/4885FABP2 176/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.