Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 2/20 | 0.73 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.73 |
| ▸ | P2RY2 | P41231 | 5/20 | 0.46 |
| ▸ | P2RY4 | P51582 | 3/20 | 0.46 |
| ▸ | BTN3A1 | O00481 | 1/20 | 0.40 |
| ▸ | P2RY14 | Q15391 | 6/20 | 0.39 |
| ▸ | P2RY6 | Q15077 | 5/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21418460 | 1.00 | CYP3A4 (0.73) | CYP3A4CYP2C9P2RY2P2RY4BTN3A1 | |
| SCHEMBL26975971 | 1.00 | CYP3A4 (0.73) | CYP3A4CYP2C9P2RY2P2RY4BTN3A1 | |
| SCHEMBL16575520 | 1.00 | CYP3A4 (0.73) | CYP3A4CYP2C9P2RY2P2RY4BTN3A1 | |
| SCHEMBL26976365 | 1.00 | CYP3A4 (0.73) | CYP3A4CYP2C9P2RY2P2RY4BTN3A1 | |
| SCHEMBL16575522 | 1.00 | CYP3A4 (0.73) | CYP3A4CYP2C9P2RY2P2RY4BTN3A1 | |
| SCHEMBL21418671 | 1.00 | CYP3A4 (0.73) | CYP3A4CYP2C9P2RY2P2RY4BTN3A1 | |
| SCHEMBL16575521 | 1.00 | CYP3A4 (0.73) | CYP3A4CYP2C9P2RY2P2RY4BTN3A1 | |
| SCHEMBL21418462 | 1.00 | CYP3A4 (0.73) | CYP3A4CYP2C9P2RY2P2RY4BTN3A1 | |
| SCHEMBL21418609 | 0.94 | CYP3A4 (0.65) | CYP3A4CYP2C9P2RY2P2RY4BTN3A1 | |
| SCHEMBL16576320 | 0.94 | CYP3A4 (0.65) | CYP3A4CYP2C9P2RY2P2RY4BTN3A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11857560-B2 | Pharmaceutical compositions comprising substituted nucleotides and nucleosides for treating viral infections | EMORY UNIVERSITY (US) | 2024-01-02 | — | — | US | disclosed |
| US-11166973-B2 | Substituted nucleotides and nucleosides for treating viral infections | EMORY UNIVERSITY (US) | 2021-11-09 | — | — | US | disclosed |
| US-20190298750-A1 | Nucleotide and Nucleoside Therapeutic Compositions and Uses Related Thereto | DEFENSE THREAT REDUCTION AGENCY, US DOD | 2019-10-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11166973-B2 | Substituted nucleotides and nucleosides for treating viral infections | PNP, TYMP, HPRT1 | CYP3A4 2565/4885CYP2C9 2155/4885P2RY2 316/4885 |
| US-11857560-B2 | Pharmaceutical compositions comprising substituted nucleotides and nucleosides for treating viral infections | SLC28A1, PNP, SLC28A2 | CYP3A4 2123/4885CYP2C9 1374/4885P2RY2 89/4885 |
| US-20190298750-A1 | Nucleotide and Nucleoside Therapeutic Compositions and Uses Related Thereto | PNP, NTPCR, TYMP | CYP3A4 4033/4885CYP2C9 3766/4885P2RY2 452/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.