SCHEMBL21423319

SCHEMBL21423319

Cc1cc2c(cc1C#N)c(-c1cccc(N)c1C)cn2-c1ccc(O)cc1

nearest known ligand 0.60

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
▸ KDM1A O60341 20/20 0.60

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20025709 0.88 KDM1A (0.73) KDM1A
SCHEMBL20604586 0.84 KDM1A (0.77) KDM1A
SCHEMBL20843800 0.78 KDM1A (0.71) KDM1A
SCHEMBL20843876 0.77 KDM1A (0.84) KDM1A
SCHEMBL20843832 0.76 KDM1A (0.83) KDM1A
SCHEMBL20025743 0.75 KDM1A (1.00) KDM1A
SCHEMBL20025684 0.75 KDM1A (1.00) KDM1A
SCHEMBL20604661 0.75 KDM1A (1.00) KDM1A
SCHEMBL22359970 0.75 KDM1A (0.74) KDM1A
SCHEMBL20843803 0.75 KDM1A (0.80) KDM1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20190298715-A1 IMMUNE EFFECTOR CELL THERAPIES WITH ENHANCED EFFICACY CHINA NOVARTIS INSTITUTES FOR BIOMEDICAL RESEARCH CO., LTD (CL) 2019-10-03 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190298715-A1 IMMUNE EFFECTOR CELL THERAPIES WITH ENHANCED EFFICACY KDM1B, KDM1A, KDM2A KDM1A 2/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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