Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM1 | Q13255 | 11/20 | 0.50 |
| ▸ | GPR119 | Q8TDV5 | 3/20 | 0.50 |
| ▸ | GRM5 | P41594 | 11/20 | 0.45 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.43 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.41 |
| ▸ | NAMPT | P43490 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31334406 | 0.85 | GRM5 (0.55) | GRM1GPR119GRM5PDK4NAMPT | |
| SCHEMBL19992989 | 0.83 | GRM1 (0.56) | GRM1GPR119GRM5PDK4NAMPT | |
| SCHEMBL19513960 | 0.81 | GRM1 (0.43) | GRM1GRM5PDK4NAMPTPOLB | |
| SCHEMBL16554636 | 0.80 | GRM1 (0.42) | GRM1GRM5PDK4NAMPT | |
| SCHEMBL30463486 | 0.80 | MEN1 (0.43) | GRM1GRM5PDK4NAMPTPOLB | |
| SCHEMBL18741854 | 0.80 | MEN1 (0.43) | GRM1GRM5PDK4NAMPTPOLB | |
| SCHEMBL23791266 | 0.79 | GRM5 (0.48) | GRM1GPR119GRM5PDK4NAMPT | |
| SCHEMBL31283768 | 0.78 | GRM1 (0.42) | GRM1GPR119GRM5PDK4NAMPT | |
| SCHEMBL2280613 | 0.78 | GRM1 (0.44) | GRM1GRM5PDK4NAMPT | |
| SCHEMBL24793826 | 0.77 | GRM1 (0.44) | GRM1GPR119GRM5PDK4NAMPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019186164-A1 | FACTOR XIIA INHIBITORS | UNIVERSITY OF LEEDS (GB) | 2019-10-03 | — | — | WO | disclosed |