Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC3 | O15379 | 5/20 | 0.48 |
| ▸ | HDAC1 | Q13547 | 5/20 | 0.48 |
| ▸ | HDAC8 | Q9BY41 | 5/20 | 0.48 |
| ▸ | HDAC2 | Q92769 | 4/20 | 0.46 |
| ▸ | HDAC10 | Q969S8 | 4/20 | 0.46 |
| ▸ | HDAC11 | Q96DB2 | 4/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.46 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.46 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.46 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.46 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.46 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.46 |
| ▸ | TACR2 | P21452 | 9/20 | 0.45 |
| ▸ | GHSR | Q92847 | 1/20 | 0.42 |
| ▸ | ROR1 | Q01973 | 1/20 | 0.42 |
| ▸ | IDO1 | P14902 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21428930 | 0.96 | TACR2 (0.48) | HDAC3HDAC1HDAC8TACR2GHSR | |
| SCHEMBL21429011 | 0.96 | TACR2 (0.48) | HDAC3HDAC1HDAC8TACR2GHSR | |
| SCHEMBL21430232 | 0.94 | HDAC8 (0.46) | HDAC3HDAC1HDAC8HDAC2HDAC10 | |
| SCHEMBL25901393 | 0.92 | HDAC3 (0.44) | HDAC3HDAC1HDAC8HDAC2HDAC10 | |
| SCHEMBL22928996 | 0.89 | TACR2 (0.40) | HDAC8TACR2GHSRROR1 | |
| SCHEMBL21428942 | 0.83 | HDAC8 (0.46) | HDAC3HDAC1HDAC8HDAC2HDAC10 | |
| SCHEMBL30538860 | 0.80 | TACR2 (0.56) | HDAC3HDAC1HDAC8TACR2ROR1 | |
| SCHEMBL21429006 | 0.80 | TACR2 (0.56) | HDAC3HDAC1HDAC8TACR2ROR1 | |
| SCHEMBL21428995 | 0.79 | POLB (0.46) | HDAC3HDAC1HDAC8HDAC2HDAC10 | |
| SCHEMBL21430235 | 0.79 | HDAC8 (0.46) | HDAC3HDAC1HDAC8HDAC2HDAC10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11713339-B2 | Macrocyclization of peptidomimetics | UNIVERSITY OF WARWICK (GB) | 2023-08-01 | — | — | US | disclosed |
| US-20210024579-A1 | MACROCYCLIZATION OF PEPTIDOMIMETICS | UNIVERSITY OF WARWICK (GB) | 2021-01-28 | — | — | US | disclosed |
| WO-2019186174-A1 | MACROCYCLIZATION OF PEPTIDOMIMETICS | UNIVERSITY OF WARWICK (GB) | 2019-10-03 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210024579-A1 | MACROCYCLIZATION OF PEPTIDOMIMETICS | NGLY1, MAX, VIP | HDAC3 2095/4885HDAC1 2555/4885HDAC8 3477/4885 |
| US-11713339-B2 | Macrocyclization of peptidomimetics | NGLY1, MAX, PTMA | HDAC3 2187/4885HDAC1 1851/4885HDAC8 2773/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.