Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 9/20 | 0.79 |
| ▸ | MET | P08581 | 1/20 | 0.79 |
| ▸ | ALK | Q9UM73 | 11/20 | 0.71 |
| ▸ | INSR | P06213 | 3/20 | 0.62 |
| ▸ | IGF1R | P08069 | 3/20 | 0.62 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.60 |
| ▸ | ZAP70 | P43403 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25299463 | 0.93 | ALK (0.72) | EGFRMETALKLRRK2ZAP70 | |
| SCHEMBL26495709 | 0.90 | EGFR (0.67) | EGFRMETALKINSRIGF1R | |
| SCHEMBL29059805 | 0.89 | EGFR (0.78) | EGFRMETALKINSRIGF1R | |
| Hydrochloric Acid SCHEMBL25261966 | 0.89 | EGFR (0.66) | EGFRMETALKINSRIGF1R | |
| SCHEMBL21432428 | 0.89 | ALK (0.73) | EGFRMETALKINSRIGF1R | |
| SCHEMBL26500041 | 0.88 | EGFR (0.65) | EGFRMETALKZAP70 | |
| SCHEMBL30497500 | 0.88 | EGFR (0.65) | EGFRMETALKZAP70 | |
| SCHEMBL21432183 | 0.88 | EGFR (1.00) | EGFRMETALKINSRIGF1R | |
| SCHEMBL21432250 | 0.88 | EGFR (0.94) | EGFRMETALKINSRIGF1R | |
| SCHEMBL25306773 | 0.88 | EGFR (0.77) | EGFRMETALKLRRK2ZAP70 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019190259-A1 | NOVEL SULFONAMIDE DERIVATIVE HAVING INHIBITORY EFFECT ON EPIDERMAL GROWTH FACTOR RECEPTOR MUTATION | 한미약품 주식회사 | 2019-10-03 | — | — | WO | disclosed |