Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.32 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | ACE | P12821 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20773853 | 0.69 | SLC6A2 (0.32) | KMT2AMEN1 | |
| SCHEMBL20773854 | 0.69 | SLC6A2 (0.32) | KMT2AMEN1 | |
| SCHEMBL20773807 | 0.67 | — | — | |
| SCHEMBL20773949 | 0.67 | — | — | |
| SCHEMBL20773805 | 0.67 | — | — | |
| SCHEMBL20776387 | 0.67 | — | — | |
| SCHEMBL21454696 | 0.67 | — | — | |
| SCHEMBL24805274 | 0.64 | KDM4E (0.31) | — | |
| SCHEMBL24804545 | 0.64 | KDM4E (0.31) | — | |
| SCHEMBL21454411 | 0.64 | KDM4E (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019194858-A1 | MODULAR SYNTHESIS OF AMINOGLYCOSIDES | ACHAOGEN, INC. (US) | 2019-10-10 | — | — | WO | disclosed |