Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 2/20 | 0.53 |
| ▸ | TLR8 | Q9NR97 | 4/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | EHMT2 | Q96KQ7 | 2/20 | 0.46 |
| ▸ | EHMT1 | Q9H9B1 | 1/20 | 0.46 |
| ▸ | PLAU | P00749 | 1/20 | 0.45 |
| ▸ | BRD4 | O60885 | 1/20 | 0.45 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21437313 | 1.00 | BACE1 (0.53) | BACE1TLR8NPC1RAB9ASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL28524052 | 0.99 | BACE1 (0.52) | BACE1TLR8NPC1RAB9ASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL21438782 | 0.99 | BACE1 (0.52) | BACE1TLR8NPC1RAB9ASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL21437184 | 0.99 | BACE1 (0.52) | BACE1TLR8NPC1RAB9ASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL21437330 | 0.99 | BACE1 (0.52) | BACE1TLR8NPC1RAB9ASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL28525259 | 0.99 | BACE1 (0.52) | BACE1TLR8NPC1RAB9ASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL21437376 | 0.99 | BACE1 (0.52) | BACE1TLR8NPC1RAB9ASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL28518967 | 0.99 | BACE1 (0.52) | BACE1TLR8NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL26451911 | 0.88 | NPC1 (0.52) | BACE1NPC1RAB9ASMN1; SMN2LMNA | |
| Hydrochloric Acid SCHEMBL21437413 | 0.86 | EHMT2 (0.55) | TLR8EHMT2EHMT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3774740-A2 | SUBSTITUTED 2-AMINOBENZIMIDAZOLES ANALOGS AS ANTIBIOFILM AGENTS | Ohio State Innovation Foundation (US) | 2021-02-17 | — | — | EP | disclosed |
| WO-2019195493-A2 | SUBSTITUTED 2-AMINOBENZIMIDAZOLES ANALOGS AS ANTIBIOFILM AGENTS | OHIO STATE INNOVATION FOUNDATION (US) | 2019-10-10 | — | — | WO | disclosed |