SCHEMBL21440358

SCHEMBL21440358

CCOC(=O)c1ccc(C(=O)OCC)cc1.[SiH4]

nearest known ligand 0.79

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 P00915 4/20 0.79
CA2 P00918 4/20 0.79
CA12 O43570 3/20 0.79
CA7 P43166 3/20 0.79
CA9 Q16790 3/20 0.79
CA14 Q9ULX7 3/20 0.79
ESR1 P03372 1/20 0.79
ESR2 Q92731 1/20 0.79
LMNA P02545 1/20 0.76
CYP1A2 P05177 1/20 0.76
CYP3A4 P08684 1/20 0.76
MAOA P21397 1/20 0.76
HPGD P15428 4/20 0.66
HTT P42858 2/20 0.66
MEN1 O00255 2/20 0.61
KMT2A Q03164 2/20 0.61
HSD17B2 P37059 1/20 0.61
RECQL P46063 1/20 0.61
ALDH1A1 P00352 1/20 0.61
HSP90AA1 P07900 1/20 0.61

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL87450 0.97 CA1 (0.83) CA1CA2CA12CA7CA9
SCHEMBL27647420 0.95 CA1 (0.79) CA1CA2CA12CA7CA9
SCHEMBL27667923 0.95 CA1 (0.79) CA1CA2CA12CA7CA9
SCHEMBL27667917 0.95 CA1 (0.79) CA1CA2CA12CA7CA9
SCHEMBL30271267 0.95 CA1 (0.79) CA1CA2CA12CA7CA9
SCHEMBL7746905 0.95 CA1 (0.79) CA1CA2CA12CA7CA9
SCHEMBL29504635 0.95 CA1 (0.79) CA1CA2CA12CA7CA9
SCHEMBL27647500 0.95 CA1 (0.79) CA1CA2CA12CA7CA9
SCHEMBL27647572 0.95 CA1 (0.79) CA1CA2CA12CA7CA9
SCHEMBL27667926 0.95 CA1 (0.79) CA1CA2CA12CA7CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2019194495-A1 POLYCYCLOHEXYLENEDIMETHYLENE TEREPHTHALATE RESIN, PREPARATION METHOD THEREFOR, AND FIBER COMPRISING SAME 에스케이케미칼 주식회사 2019-10-10 WO disclosed