Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.34 |
| ▸ | MCHR1 | Q99705 | 4/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.31 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.31 |
| ▸ | CDK2 | P24941 | 1/20 | 0.31 |
| ▸ | CDK9 | P50750 | 1/20 | 0.31 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12608666 | 0.80 | MCHR1 (0.45) | CNR2ALDH1A1MCHR1MEN1KMT2A | |
| SCHEMBL12608664 | 0.76 | CNR2 (0.46) | CNR2ALDH1A1SCN9AMAPTTHRB | |
| SCHEMBL21441047 | 0.75 | CNR2 (0.34) | CNR2ALDH1A1MCHR1MEN1KMT2A | |
| SCHEMBL12608663 | 0.74 | CNR2 (0.44) | CNR2ALDH1A1MCHR1MEN1KMT2A | |
| SCHEMBL12608660 | 0.73 | CNR2 (0.43) | CNR2ALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL20828077 | 0.72 | KDM4E (0.41) | ALDH1A1MEN1KMT2AMAPTTP53 | |
| SCHEMBL12608658 | 0.72 | CNR2 (0.44) | CNR2ALDH1A1MCHR1MEN1KMT2A | |
| SCHEMBL12608659 | 0.71 | CNR2 (0.44) | CNR2ALDH1A1MCHR1TP53POLB | |
| SCHEMBL12608665 | 0.71 | CNR2 (0.45) | CNR2ALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL12608637 | 0.70 | CNR2 (0.51) | CNR2ALDH1A1MEN1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2294186-B1 | INDUCING CELL DEATH BY INHIBITING ADAPTIVE HEAT SHOCK RESPONSE | INCURON INC (US) | 2019-10-09 | — | — | EP | disclosed |