Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTNNB1 | P35222 | 9/20 | 0.51 |
| ▸ | WNT3A | P56704 | 9/20 | 0.51 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.37 |
| ▸ | PPARG | P37231 | 2/20 | 0.37 |
| ▸ | F2 | P00734 | 1/20 | 0.36 |
| ▸ | ULK1 | O75385 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.33 |
| ▸ | PRKCI | P41743 | 1/20 | 0.33 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21441370 | 0.85 | CTNNB1 (0.48) | CTNNB1WNT3AF2CYP1A2CYP3A4 | |
| SCHEMBL21441429 | 0.83 | CTNNB1 (0.53) | CTNNB1WNT3A | |
| SCHEMBL21441304 | 0.83 | CTNNB1 (0.48) | CTNNB1WNT3AF2CYP1A2CYP3A4 | |
| SCHEMBL15988724 | 0.82 | CTNNB1 (0.69) | CTNNB1WNT3AEPHX2PPARG | |
| SCHEMBL21441201 | 0.81 | CTNNB1 (0.67) | CTNNB1WNT3AEPHX2PPARGF2 | |
| SCHEMBL21441268 | 0.80 | CTNNB1 (0.53) | CTNNB1WNT3AF2CYP1A2CYP3A4 | |
| SCHEMBL21441426 | 0.78 | CTNNB1 (0.51) | CTNNB1WNT3A | |
| SCHEMBL21441180 | 0.77 | CTNNB1 (0.48) | CTNNB1WNT3AEPHX2PPARGF2 | |
| SCHEMBL21441225 | 0.76 | CTNNB1 (0.48) | CTNNB1WNT3AF2CYP1A2CYP3A4 | |
| SCHEMBL21441306 | 0.75 | CTNNB1 (0.49) | CTNNB1WNT3AF2CYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3206686-B1 | GAMMA-DIKETONES FOR TREATMENT AND PREVENTION OF AGING SKIN AND WRINKLES | SAMUMED LLC (US) | 2019-10-09 | — | — | EP | disclosed |