SCHEMBL2144143

SCHEMBL2144143

CCCCCOC(=O)/C=C\C(=O)O[Si](CCCCC)(CCCCC)CCCCC

nearest known ligand 0.62

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
HCAR2 Q8TDS4 4/20 0.62
ATM Q13315 1/20 0.61
MAPT P10636 1/20 0.51
RAB9A P51151 1/20 0.51
NPSR1 Q6W5P4 1/20 0.51
HPGD P15428 1/20 0.44
TSHR P16473 1/20 0.44
APP P05067 4/20 0.43
NAAA Q02083 1/20 0.42
HTT P42858 2/20 0.41
SMN1; SMN2 Q16637 2/20 0.41
EPHX1 P07099 1/20 0.40
PRKCA P17252 2/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL476058 0.98 HCAR2 (0.63) HCAR2ATMMAPTRAB9ANPSR1
SCHEMBL476059 0.98 HCAR2 (0.63) HCAR2ATMMAPTRAB9ANPSR1
SCHEMBL2144590 0.98 HCAR2 (0.63) HCAR2ATMMAPTRAB9ANPSR1
SCHEMBL2144665 0.98 HCAR2 (0.63) HCAR2ATMMAPTRAB9ANPSR1
SCHEMBL2144186 0.98 HCAR2 (0.63) HCAR2ATMMAPTRAB9ANPSR1
SCHEMBL476076 0.98 HCAR2 (0.63) HCAR2ATMMAPTRAB9ANPSR1
SCHEMBL2144179 0.98 HCAR2 (0.63) HCAR2ATMMAPTRAB9ANPSR1
SCHEMBL2144670 0.98 HCAR2 (0.63) HCAR2ATMMAPTRAB9ANPSR1
SCHEMBL5974572 0.95 HCAR2 (0.63) HCAR2ATMMAPTRAB9ANPSR1
SCHEMBL5974155 0.95 HCAR2 (0.63) HCAR2ATMMAPTRAB9ANPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2348077-B1 Antifouling composition JOTUN AS (NO) 2013-04-03 EP disclosed
EP-2348077-A1 Antifouling composition Jotun A/S (NO) 2011-07-27 EP disclosed
EP-0802243-B1 Coating composition NOF CORP (JP) 2001-06-27 EP disclosed
US-5795374-A SILYL ACRYLATE POLYMERS NOF CORPORATION (JP) 1998-08-18 US disclosed
EP-0802243-A2 Coating composition NOF CORPORATION (JP) 1997-10-22 EP disclosed