Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15991675 | 1.00 | BACE1 (0.46) | BACE1 | |
| SCHEMBL15991228 | 1.00 | BACE1 (0.46) | BACE1 | |
| SCHEMBL15991231 | 1.00 | BACE1 (0.46) | BACE1 | |
| SCHEMBL15991676 | 1.00 | BACE1 (0.46) | BACE1 | |
| SCHEMBL15991229 | 1.00 | BACE1 (0.46) | BACE1 | |
| SCHEMBL15991245 | 0.84 | BACE1 (0.36) | BACE1 | |
| SCHEMBL15991242 | 0.84 | BACE1 (0.36) | BACE1 | |
| SCHEMBL15991247 | 0.84 | BACE1 (0.36) | BACE1 | |
| SCHEMBL15991009 | 0.84 | BACE1 (0.44) | BACE1 | |
| SCHEMBL21442321 | 0.84 | BACE1 (0.44) | BACE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2961749-B1 | PERFLUORINATED 5,6-DIHYDRO-4H-1,3-OXAZIN-2-AMINE COMPOUNDS AS BETA-SECRETASE INHIBITORS AND METHODS OF USE | AMGEN INC (US) | 2019-10-09 | — | — | EP | disclosed |