Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SYK | P43405 | 11/20 | 0.75 |
| ▸ | AURKA | O14965 | 4/20 | 0.60 |
| ▸ | EGFR | P00533 | 4/20 | 0.60 |
| ▸ | ITK | Q08881 | 2/20 | 0.60 |
| ▸ | KDR | P35968 | 1/20 | 0.56 |
| ▸ | BCL6 | P41182 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12726123 | 0.88 | SYK (0.74) | SYKAURKAEGFRITKKDR | |
| SCHEMBL31294266 | 0.87 | SYK (1.00) | SYKAURKAEGFRITKKDR | |
| SCHEMBL656171 | 0.87 | SYK (1.00) | SYKAURKAEGFRITKKDR | |
| SCHEMBL12519588 | 0.86 | EGFR (0.72) | SYKEGFRITK | |
| Hydrochloric Acid SCHEMBL653397 | 0.85 | SYK (0.97) | SYKAURKAEGFRITKKDR | |
| SCHEMBL4935602 | 0.85 | SYK (0.97) | SYKAURKAEGFRITKKDR | |
| Hydrochloric Acid SCHEMBL653396 | 0.84 | SYK (0.94) | SYKAURKAEGFRITKKDR | |
| SCHEMBL12519594 | 0.84 | EGFR (0.71) | SYKEGFRITK | |
| SCHEMBL13166587 | 0.83 | SYK (0.66) | SYKEGFRITK | |
| SCHEMBL21443466 | 0.83 | ABCG2 (0.58) | SYKAURKAEGFRITK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3549934-A1 | HETEROARYL COMPOUNDS AND USES THEREOF | Celgene CAR LLC (BM) | 2019-10-09 | — | — | EP | disclosed |