Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 11/20 | 0.81 |
| ▸ | BTK | Q06187 | 6/20 | 0.81 |
| ▸ | SYK | P43405 | 8/20 | 0.72 |
| ▸ | ITK | Q08881 | 3/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29722225 | 0.89 | EGFR (1.00) | EGFRBTKSYKITK | |
| SCHEMBL12518577 | 0.89 | EGFR (1.00) | EGFRBTKSYKITK | |
| SCHEMBL12518388 | 0.89 | EGFR (1.00) | EGFRBTKSYKITK | |
| SCHEMBL29722222 | 0.88 | EGFR (1.00) | EGFRBTKSYKITK | |
| SCHEMBL12518655 | 0.88 | EGFR (1.00) | EGFRBTKSYKITK | |
| SCHEMBL655971 | 0.85 | SYK (1.00) | BTKSYKITK | |
| SCHEMBL12518419 | 0.81 | BTK (1.00) | EGFRBTKSYKITK | |
| SCHEMBL29722440 | 0.81 | BTK (1.00) | EGFRBTKSYKITK | |
| SCHEMBL24486568 | 0.81 | EGFR (0.81) | EGFRBTKSYKITK | |
| SCHEMBL14769302 | 0.80 | EGFR (0.80) | EGFRBTKSYKITK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3549934-A1 | HETEROARYL COMPOUNDS AND USES THEREOF | Celgene CAR LLC (BM) | 2019-10-09 | — | — | EP | disclosed |