Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 20/20 | 0.79 |
| ▸ | BRD2 | P25440 | 1/20 | 0.61 |
| ▸ | EP300 | Q09472 | 1/20 | 0.61 |
| ▸ | BRD3 | Q15059 | 1/20 | 0.61 |
| ▸ | BRDT | Q58F21 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18075356 | 0.93 | BRD4 (0.79) | BRD4BRD2EP300BRD3BRDT | |
| SCHEMBL18075095 | 0.93 | BRD4 (0.79) | BRD4BRD2EP300BRD3BRDT | |
| SCHEMBL18075098 | 0.93 | BRD4 (0.79) | BRD4BRD2EP300BRD3BRDT | |
| SCHEMBL21010231 | 0.93 | BRD4 (0.78) | BRD4BRD2EP300BRD3BRDT | |
| SCHEMBL21010230 | 0.93 | BRD4 (0.78) | BRD4BRD2EP300BRD3BRDT | |
| SCHEMBL21009920 | 0.93 | BRD4 (0.78) | BRD4BRD2EP300BRD3BRDT | |
| SCHEMBL18075551 | 0.91 | BRD4 (0.74) | BRD4BRD2EP300BRD3BRDT | |
| SCHEMBL18075548 | 0.91 | BRD4 (0.74) | BRD4BRD2EP300BRD3BRDT | |
| SCHEMBL20969007 | 0.89 | BRD4 (0.79) | BRD4BRD2EP300BRD3BRDT | |
| SCHEMBL19857943 | 0.89 | BRD4 (0.79) | BRD4BRD2EP300BRD3BRDT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3549939-A1 | BENZIMIDAZOLE DERIVATIVES AS BROMODOMAIN INHIBITORS | GlaxoSmithKline Intellectual Property Development Limited (GB) | 2019-10-09 | — | — | EP | disclosed |