SCHEMBL2144673

SCHEMBL2144673

CCCC[CH][Si](CCCCC)(CCCCC)CCCCC

nearest known ligand 0.38

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
TSHR P16473 6/20 0.38
ALDH1A1 P00352 1/20 0.38
THRB P10828 1/20 0.35
DNM1 Q05193 3/20 0.33
FAAH O00519 2/20 0.31
TRPV1 Q8NER1 1/20 0.31
TOP1 P11387 2/20 0.30
LMNA P02545 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2144174 0.92 TSHR (0.44) TSHRTHRBDNM1FAAHTRPV1
SCHEMBL686670 0.84 TSHR (0.40) TSHRALDH1A1THRBDNM1FAAH
SCHEMBL2144494 0.81 TSHR (0.33) TSHRALDH1A1THRBLMNA
SCHEMBL2970241 0.78 TSHR (0.41) TSHRALDH1A1THRBDNM1LMNA
SCHEMBL2968967 0.76 TSHR (0.42) TSHRALDH1A1THRBDNM1FAAH
SCHEMBL2963731 0.74 TSHR (0.46) TSHRTHRBDNM1FAAHTRPV1
SCHEMBL2962310 0.74 TSHR (0.46) TSHRTHRBDNM1FAAHTRPV1
SCHEMBL2963381 0.74 TSHR (0.46) TSHRTHRBDNM1FAAHTRPV1
SCHEMBL2972751 0.74 TSHR (0.46) TSHRTHRBDNM1FAAHTRPV1
SCHEMBL2975913 0.74 TSHR (0.46) TSHRTHRBDNM1FAAHTRPV1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2348077-B1 Antifouling composition JOTUN AS (NO) 2013-04-03 EP disclosed
EP-2348077-A1 Antifouling composition Jotun A/S (NO) 2011-07-27 EP disclosed
EP-0802243-B1 Coating composition NOF CORP (JP) 2001-06-27 EP disclosed
US-5795374-A SILYL ACRYLATE POLYMERS NOF CORPORATION (JP) 1998-08-18 US disclosed
EP-0802243-A2 Coating composition NOF CORPORATION (JP) 1997-10-22 EP disclosed