Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH4 | Q9H3N8 | 4/20 | 0.43 |
| ▸ | TOP1 | P11387 | 1/20 | 0.38 |
| ▸ | TOP2A | P11388 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 5/20 | 0.35 |
| ▸ | MAPT | P10636 | 6/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.33 |
| ▸ | TRPV1 | Q8NER1 | 3/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | TNKS | O95271 | 1/20 | 0.32 |
| ▸ | PARP1 | P09874 | 1/20 | 0.32 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21451064 | 0.84 | HRH4 (0.43) | HRH4TOP1TOP2ATP53MAPT | |
| SCHEMBL21451025 | 0.79 | TOP1 (0.58) | HRH4TOP1TOP2ATP53MAPT | |
| SCHEMBL21451005 | 0.78 | GBA1 (0.49) | HRH4TOP1TOP2ATP53 | |
| SCHEMBL30089834 | 0.76 | HRH4 (0.56) | HRH4TOP1TOP2A | |
| SCHEMBL21451020 | 0.76 | HRH4 (0.56) | HRH4TOP1TOP2A | |
| SCHEMBL21450998 | 0.75 | TOP1 (0.56) | HRH4TOP1TOP2AMAPTLMNA | |
| SCHEMBL30089860 | 0.74 | MAPT (0.51) | HRH4TOP1TOP2AMAPTLMNA | |
| SCHEMBL21451000 | 0.74 | MAPT (0.51) | HRH4TOP1TOP2AMAPTLMNA | |
| SCHEMBL21450999 | 0.74 | TOP1 (0.55) | HRH4TOP1TOP2AMAPTLMNA | |
| SCHEMBL21451019 | 0.72 | TOP1 (0.69) | HRH4TOP1TOP2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019191896-A1 | FMS-LIKE TYROSINE KINASE INHIBITORS | 3SM BIOTRON INC. (CN) | 2019-10-10 | — | — | WO | disclosed |