Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MPI | P34949 | 2/20 | 0.39 |
| ▸ | PMM2 | O15305 | 1/20 | 0.39 |
| ▸ | PHOSPHO1 | Q8TCT1 | 1/20 | 0.39 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.39 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.39 |
| ▸ | TOP1 | P11387 | 1/20 | 0.39 |
| ▸ | TOP2A | P11388 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | TLR8 | Q9NR97 | 3/20 | 0.37 |
| ▸ | TLR7 | Q9NYK1 | 3/20 | 0.37 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.36 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.36 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21450906 | 0.85 | TOP1 (0.43) | MPIPMM2PHOSPHO1APOBEC3GTLR9 | |
| SCHEMBL17655671 | 0.85 | KDM4E (0.52) | TOP1TOP2ATLR8TLR7ADORA2A | |
| SCHEMBL21875194 | 0.82 | KDM4E (0.55) | L3MBTL1ADORA2AADORA3KMT2AMEN1 | |
| SCHEMBL16374499 | 0.82 | TOP1 (0.39) | TOP1TOP2ATLR8TLR7KDM4E | |
| SCHEMBL21451024 | 0.81 | NPC1 (0.43) | KMT2AMEN1NPC1RAB9AKDM4E | |
| SCHEMBL21451006 | 0.81 | TOP1 (0.45) | MPIPMM2PHOSPHO1APOBEC3GTLR9 | |
| SCHEMBL30089850 | 0.80 | PRKCI (0.38) | TOP1TOP2AL3MBTL1GLAKDM4E | |
| SCHEMBL21875232 | 0.80 | PRKCI (0.38) | TOP1TOP2AL3MBTL1GLAKDM4E | |
| SCHEMBL21450998 | 0.79 | TOP1 (0.56) | TOP1TOP2AL3MBTL1GLATLR7 | |
| SCHEMBL21450992 | 0.78 | TOP1 (0.43) | MPIPMM2PHOSPHO1APOBEC3GTLR9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11332476-B2 | Fms-like tyrosine kinase inhibitors | 3SM BIOTRON INC. (TW) | 2022-05-17 | — | — | US | disclosed |
| US-11332476-B2 | Fms-like tyrosine kinase inhibitors | 3SM BIOTRON INC. (TW) | 2022-05-17 | — | — | US | disclosed |
| US-20200131194-A1 | FMS-LIKE TYROSINE KINASE INHIBITORS | Sagabio Co., Ltd. (TW) | 2020-04-30 | — | — | US | disclosed |
| US-20200131194-A1 | FMS-LIKE TYROSINE KINASE INHIBITORS | Sagabio Co., Ltd. (TW) | 2020-04-30 | — | — | US | disclosed |
| WO-2019191896-A1 | FMS-LIKE TYROSINE KINASE INHIBITORS | 3SM BIOTRON INC. (CN) | 2019-10-10 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11332476-B2 | Fms-like tyrosine kinase inhibitors | FLT3, FLT4, FLT1 | MPI 1310/4885PMM2 3233/4885PHOSPHO1 4512/4885 |
| US-20200131194-A1 | FMS-LIKE TYROSINE KINASE INHIBITORS | FLT3, FLT4, FLT1 | MPI 1310/4885PMM2 3233/4885PHOSPHO1 4512/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.