Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CD274 | Q9NZQ7 | 7/20 | 0.54 |
| ▸ | PDCD1 | Q15116 | 6/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CDK4 | P11802 | 1/20 | 0.37 |
| ▸ | CDK2 | P24941 | 1/20 | 0.37 |
| ▸ | CDK6 | Q00534 | 1/20 | 0.37 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31396702 | 0.88 | CD274 (0.57) | CD274PDCD1LMNASMN1; SMN2MAPT | |
| SCHEMBL22966562 | 0.85 | CD274 (0.51) | CD274PDCD1LMNASMN1; SMN2MAPT | |
| SCHEMBL12706735 | 0.85 | MAPT (0.43) | CD274PDCD1MAPTALDH1A1KDM4E | |
| SCHEMBL12706734 | 0.84 | CD274 (0.47) | CD274PDCD1MAPTALDH1A1TSHR | |
| SCHEMBL18549994 | 0.79 | PDCD1 (0.49) | CD274PDCD1LMNASMN1; SMN2MAPT | |
| SCHEMBL31576710 | 0.78 | CD274 (0.61) | CD274PDCD1 | |
| SCHEMBL7399072 | 0.77 | MAPT (0.61) | LMNASMN1; SMN2MAPTALDH1A1MAPK1 | |
| SCHEMBL18549972 | 0.76 | CD274 (0.43) | CD274PDCD1LMNASMN1; SMN2MAPT | |
| Hydrochloric Acid SCHEMBL8824760 | 0.76 | MAPT (0.60) | LMNASMN1; SMN2MAPTALDH1A1MAPK1 | |
| SCHEMBL17111549 | 0.76 | MAPT (0.46) | CD274PDCD1LMNASMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019192506-A1 | IMMUNOMODULATORS, COMPOSITIONS AND METHODS THEREOF | BETTA PHARMACEUTICALS CO., LTD (CN) | 2019-10-10 | — | — | WO | disclosed |