Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAD52 | P43351 | 2/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | GRM5 | P41594 | 6/20 | 0.41 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 4/20 | 0.35 |
| ▸ | PDCD1 | Q15116 | 2/20 | 0.35 |
| ▸ | CD274 | Q9NZQ7 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.34 |
| ▸ | MAPT | P10636 | 4/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | CASP1 | P29466 | 1/20 | 0.34 |
| ▸ | CASP7 | P55210 | 1/20 | 0.34 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.34 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12680942 | 0.78 | RAD52 (0.53) | RAD52RECQLGRM5PDE10AHRH3 | |
| SCHEMBL12680940 | 0.77 | GRM5 (0.57) | RAD52RECQLGRM5PDE10AHRH3 | |
| SCHEMBL17088067 | 0.77 | RAD52 (0.48) | RAD52RECQLGRM5PDE10AHRH3 | |
| SCHEMBL16286091 | 0.77 | RAD52 (0.48) | RAD52RECQLGRM5PDE10AHRH3 | |
| SCHEMBL16609856 | 0.76 | RAD52 (0.47) | RAD52RECQLGRM5PDE10AHRH3 | |
| SCHEMBL16609857 | 0.76 | RAD52 (0.47) | RAD52RECQLGRM5PDE10AHRH3 | |
| SCHEMBL15918533 | 0.76 | RAD52 (0.47) | RAD52RECQLGRM5PDE10AHRH3 | |
| SCHEMBL17088068 | 0.76 | RAD52 (0.47) | RAD52RECQLGRM5PDE10AHRH3 | |
| SCHEMBL21451962 | 0.75 | RAD52 (0.46) | RAD52RECQLGRM5PDE10AGAA | |
| Potassium Ion SCHEMBL16583490 | 0.75 | RAD52 (0.46) | RAD52RECQLGRM5PDE10AHRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019192506-A1 | IMMUNOMODULATORS, COMPOSITIONS AND METHODS THEREOF | BETTA PHARMACEUTICALS CO., LTD (CN) | 2019-10-10 | — | — | WO | disclosed |