Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAD52 | P43351 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 8/20 | 0.42 |
| ▸ | GAA | P10253 | 4/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 6/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 6/20 | 0.40 |
| ▸ | GRM5 | P41594 | 2/20 | 0.39 |
| ▸ | DPP4 | P27487 | 1/20 | 0.39 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.39 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.39 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21451978 | 0.89 | RAD52 (0.43) | RAD52RECQLHDAC6GAAHDAC3 | |
| SCHEMBL21452354 | 0.88 | HDAC6 (0.42) | RAD52RECQLHDAC6GAAHDAC3 | |
| SCHEMBL22966522 | 0.84 | GAA (0.41) | RAD52RECQLHDAC6GAAHDAC3 | |
| SCHEMBL16286089 | 0.81 | RAD52 (0.48) | RAD52RECQLGAAGRM5DPP4 | |
| SCHEMBL16286091 | 0.79 | RAD52 (0.48) | RAD52RECQLHDAC6GAAGRM5 | |
| SCHEMBL21451967 | 0.78 | GRM5 (0.45) | RAD52RECQLHDAC6GAAHDAC3 | |
| SCHEMBL12680942 | 0.78 | RAD52 (0.53) | RAD52RECQLGAAGRM5ALDH1A1 | |
| SCHEMBL21451962 | 0.77 | RAD52 (0.46) | RAD52RECQLGAAGRM5DPP4 | |
| SCHEMBL21451963 | 0.76 | RAD52 (0.43) | RAD52RECQLHDAC6GAAGRM5 | |
| SCHEMBL17383827 | 0.76 | RAD52 (0.48) | RAD52RECQLHDAC6HDAC3HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019192506-A1 | IMMUNOMODULATORS, COMPOSITIONS AND METHODS THEREOF | BETTA PHARMACEUTICALS CO., LTD (CN) | 2019-10-10 | — | — | WO | disclosed |