Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.49 |
| ▸ | GRM5 | P41594 | 3/20 | 0.43 |
| ▸ | RAD52 | P43351 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | DRD2 | P14416 | 2/20 | 0.37 |
| ▸ | DRD3 | P35462 | 2/20 | 0.37 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.36 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | MYC | P01106 | 1/20 | 0.35 |
| ▸ | KDM1A | O60341 | 1/20 | 0.35 |
| ▸ | TNNI3K | Q59H18 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14907151 | 0.89 | HRH3 (0.49) | HRH3DRD2DRD3KEAP1SMN1; SMN2 | |
| SCHEMBL14907159 | 0.86 | HRH3 (0.46) | HRH3DRD2DRD3KEAP1SMN1; SMN2 | |
| SCHEMBL17383827 | 0.81 | RAD52 (0.48) | HRH3GRM5RAD52RECQLDRD2 | |
| SCHEMBL12680942 | 0.80 | RAD52 (0.53) | HRH3GRM5RAD52RECQLDRD2 | |
| SCHEMBL16286091 | 0.79 | RAD52 (0.48) | HRH3GRM5RAD52RECQLDRD2 | |
| SCHEMBL21451980 | 0.78 | HRH3 (0.43) | HRH3GRM5RAD52RECQLPDE10A | |
| SCHEMBL21451967 | 0.77 | GRM5 (0.45) | HRH3GRM5RAD52RECQLSMN1; SMN2 | |
| SCHEMBL21451976 | 0.76 | HRH3 (0.47) | HRH3GRM5RAD52RECQLDRD2 | |
| SCHEMBL12344273 | 0.76 | HRH3 (0.47) | HRH3GRM5RAD52RECQLDRD2 | |
| SCHEMBL6369558 | 0.76 | RAD52 (0.69) | HRH3GRM5RAD52RECQLPDE10A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019192506-A1 | IMMUNOMODULATORS, COMPOSITIONS AND METHODS THEREOF | BETTA PHARMACEUTICALS CO., LTD (CN) | 2019-10-10 | — | — | WO | disclosed |