Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDCD1 | Q15116 | 7/20 | 0.36 |
| ▸ | CD274 | Q9NZQ7 | 7/20 | 0.36 |
| ▸ | PNMT | P11086 | 1/20 | 0.33 |
| ▸ | PDK1 | Q15118 | 3/20 | 0.32 |
| ▸ | FBP1 | P09467 | 2/20 | 0.32 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.32 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.32 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.32 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.32 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.32 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.30 |
| ▸ | OGA | O60502 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL330205 | 0.89 | PDCD1 (0.44) | PDCD1CD274PNMTTLR9TLR8 | |
| Hydrochloric Acid SCHEMBL6765448 | 0.87 | PDCD1 (0.43) | PDCD1CD274PNMTTLR9TLR8 | |
| Bromide SCHEMBL3822772 | 0.87 | PDCD1 (0.43) | PDCD1CD274PNMTTLR9TLR8 | |
| SCHEMBL2846333 | 0.78 | — | — | |
| SCHEMBL12101179 | 0.78 | APOBEC3A (0.58) | PDK1FBP1APOBEC3AAPOBEC3G | |
| SCHEMBL22966476 | 0.77 | PDCD1 (0.32) | PDCD1CD274PDK1FBP1APOBEC3A | |
| SCHEMBL15910247 | 0.77 | PDCD1 (0.48) | PDCD1CD274PNMTTLR9TLR7 | |
| SCHEMBL31143437 | 0.76 | PDCD1 (0.39) | PDCD1CD274PNMTTLR9TLR8 | |
| Bromide SCHEMBL3309184 | 0.76 | APOBEC3A (0.56) | APOBEC3AAPOBEC3G | |
| Bromide SCHEMBL20899228 | 0.76 | PDCD1 (0.31) | PDCD1CD274 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019192506-A1 | IMMUNOMODULATORS, COMPOSITIONS AND METHODS THEREOF | BETTA PHARMACEUTICALS CO., LTD (CN) | 2019-10-10 | — | — | WO | disclosed |