Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FUBP1 | Q96AE4 | 6/20 | 0.82 |
| ▸ | MAPT | P10636 | 8/20 | 0.57 |
| ▸ | TP53 | P04637 | 2/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | CASP1 | P29466 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 3/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21436605 | 0.90 | FUBP1 (1.00) | FUBP1MAPTTP53TDP1MAPK1 | |
| SCHEMBL30417906 | 0.90 | FUBP1 (1.00) | FUBP1MAPTTP53TDP1MAPK1 | |
| SCHEMBL30417399 | 0.79 | FUBP1 (1.00) | FUBP1MAPTTP53TDP1MAPK1 | |
| SCHEMBL21436681 | 0.79 | FUBP1 (1.00) | FUBP1MAPTTP53TDP1MAPK1 | |
| SCHEMBL17066235 | 0.75 | MAPT (0.75) | FUBP1MAPTTP53TDP1MAPK1 | |
| SCHEMBL21436636 | 0.75 | FUBP1 (1.00) | FUBP1MAPTTP53TDP1MAPK1 | |
| SCHEMBL21945408 | 0.71 | FUBP1 (0.79) | FUBP1MAPTTP53TDP1MAPK1 | |
| SCHEMBL17066234 | 0.71 | FUBP1 (0.79) | FUBP1MAPTTP53TDP1MAPK1 | |
| SCHEMBL17066463 | 0.70 | MAPT (0.77) | FUBP1MAPTTP53TDP1MAPK1 | |
| SCHEMBL12497070 | 0.70 | FUBP1 (0.54) | FUBP1MAPTMAPK1CASP1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019193165-A1 | USE OF FUBP1 INHIBITORS FOR TREATING HEPATITIS B VIRUS INFECTION | F. HOFFMANN-LA ROCHE AG (CH) | 2019-10-10 | — | — | WO | disclosed |