Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 3/20 | 0.37 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.36 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.36 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.36 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.36 |
| ▸ | DPP8 | Q6V1X1 | 2/20 | 0.35 |
| ▸ | DPP4 | P27487 | 2/20 | 0.35 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.35 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.35 |
| ▸ | DRD2 | P14416 | 5/20 | 0.35 |
| ▸ | DRD3 | P35462 | 5/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.34 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.33 |
| ▸ | RAD52 | P43351 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21451962 | 0.88 | RAD52 (0.46) | GRM5DPP8DPP4DPP9DPP7 | |
| SCHEMBL28483267 | 0.81 | DRD3 (0.38) | HRH3TLR9TLR8TLR7DRD2 | |
| SCHEMBL24202747 | 0.76 | ADORA2A (0.43) | HRH3DRD2DRD3ADORA2ARAD52 | |
| SCHEMBL16286089 | 0.75 | RAD52 (0.48) | GRM5TLR9TLR8TLR7DPP8 | |
| SCHEMBL21451975 | 0.73 | TLR9 (0.48) | GRM5TLR9TLR8TLR7DPP8 | |
| SCHEMBL21451963 | 0.73 | RAD52 (0.43) | GRM5TLR9TLR8TLR7DPP8 | |
| SCHEMBL21451967 | 0.72 | GRM5 (0.45) | GRM5HRH3DPP8DPP4DPP9 | |
| SCHEMBL28483068 | 0.71 | RAD52 (0.42) | GRM5HRH3DRD3GAARAD52 | |
| SCHEMBL14907151 | 0.70 | HRH3 (0.49) | HRH3DRD2DRD3GAAADORA2A | |
| SCHEMBL14907159 | 0.70 | HRH3 (0.46) | HRH3TLR8TLR7DRD2DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019192506-A1 | IMMUNOMODULATORS, COMPOSITIONS AND METHODS THEREOF | BETTA PHARMACEUTICALS CO., LTD (CN) | 2019-10-10 | — | — | WO | disclosed |